Chemical Constituents from the Fruit Bodies of Lentinula edodes

표고(Lentinula edodes) 자실체의 추출성분

  • Lee, Hak-Ju (Div. Wood Chemistry & Microbiology, Korea Forest Research Institute) ;
  • Yoon, Kab-Hee (Div. Wood Chemistry & Microbiology, Korea Forest Research Institute) ;
  • Bak, Won-Chull (Div. Wood Chemistry & Microbiology, Korea Forest Research Institute)
  • 이학주 (임업연구원 화학미생물과) ;
  • 윤갑희 (임업연구원 화학미생물과) ;
  • 박원철 (임업연구원 화학미생물과)
  • Received : 2002.06.19
  • Accepted : 2002.07.31
  • Published : 2003.04.26

Abstract

Three nucleotides, one amide, acid and steroid, were isolated from the fruit bodies of Lentinula edodes. The structures were determined as adenosine (9-𝛽-D-ribofuranosyladenine), uridine (1-𝛽-D-ribofuranosyluracil), uracil (2, 4-pyrimidinedione), nicotinamide, p-hydroxybenzoic acid and ergosterol (ergosta-5, 7, 22-triene-3𝛽-ol), respectively, on the basis of spectroscopic data and chemical correlations.

표고(Lentinula edodes) 자실체의 메탄올(methanol, MeOH) 조추출물로부터 활성성분을 탐색하는 과정에서 6개의 화합물을 분리하였으며, 단리물질은 nucleotide인 uracil(2, 4-pyrimidinedione)를 비롯하여 adenosine(9-𝛽-D-ribofuranosyladenine), uridine(1-𝛽-D-ribofuranosyluracil)과, amide 화합물인 nicotinamide, 그리고 p-hydroxybenzoic acid, ergosterol(ergosta-5, 7, 22-triene-3𝛽-ol)으로 각각 동정하였다.

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