fMRI study on the cerebral activity induced by Electro-acupuncture on Sanyinjiao(Sp6)

삼음교(三陰交)(Sp6) 전침자극(電針刺戟)이 fMRI상 뇌활성변화(腦活性變化)에 미치는 영향(影響)

  • Hong, Kwon-eui (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Dae-Jeon University) ;
  • Lee, Byung-ryul (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Dae-Jeon University) ;
  • Lee, Hyun (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Dae-Jeon University) ;
  • Yim, Yun-kyoung (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Dae-Jeon University) ;
  • Kim, Yun-jin (Department of Diagnostic Radiology Hae-Hwa Hospital, Dae-Jeon University)
  • 홍권의 (대전대학교 한의과대학 침구경혈학교실) ;
  • 이병렬 (대전대학교 한의과대학 침구경혈학교실) ;
  • 이현 (대전대학교 한의과대학 침구경혈학교실) ;
  • 임윤경 (대전대학교 한의과대학 침구경혈학교실) ;
  • 김연진 (대전대학교부속 혜화병원 진단방사선과)
  • Received : 2003.05.12
  • Accepted : 2003.05.17
  • Published : 2003.06.20

Abstract

Objective : Recently, many studies have showed the evidences of the effect of the acupunture treatment through scientific methods. One of these methods is functional MRI. We performed electro-acupunture on Sp6 and observed the changes of brain activation using fMRI. Methods : To see the effect of electro-acupunture stimulation on Sp6, the experiment was carried out on 12 healthy volunteers, using the gradient echo sequence with the 3.0T whole-body MRI system(ISOL). After the needle insertion on right Sp6, 2Hz of electric stimulation was given for 30 seconds, repeated five times, with 30 seconds' intervals. The Image analysis including motion correction, talairach transformation, and smoothing was done with SPM99. Results : 1. Group averaged brain activation induced by bilateral eletro-acupunture stimulation on Sp6 activates Brodman Area 3, 7, 13. 2. Group averaged brain deactivation induced by bilateral eletro-acupunture stimulation on Sp6 activates Brodman Area 6, 38, 47. 3. Group averaged brain activation induced by unilateral(right side) eletro-acupunture stimulation on Sp6 activates Brodman Area 5, 6, 13, 17, 18, 19, 31, 38, 40 ptoms, back pain(32.5%) was the 4. Group averaged brain deactivation induced by unilateral(right side) eletro-acupunture stimulation on Sp6 activates Brodman Area 3, 4, 18, 21, 36, 38, 39. 5. Brain region activated by motor stimulation activates Brodman Area 3, 4, 6, 18, 19.

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