The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
권호 표지

Effects of Liriopis Tuber on Starvation Stress in Mice

맥문동이 생쥐의 기아 스트레스에 미치는 영향

  • Jeon Sung-Ha (Department of Internal Medicine, College of Oriental Medicine, Kyungwon University) ;
  • Baek Eun-Ki (Department of Internal Medicine, College of Oriental Medicine, Kyungwon University) ;
  • Hong Yi-Sil (Department of Internal Medicine, College of Oriental Medicine, Kyungwon University) ;
  • Park Jhee-Yoon (Department of Internal Medicine, College of Oriental Medicine, Kyungwon University) ;
  • Han Jhee-Wan (Department of Internal Medicine, College of Oriental Medicine, Kyungwon University) ;
  • Yim Young-Nam (Department of Internal Medicine, College of Oriental Medicine, Kyungwon University) ;
  • Ko Ho-Yeon (Department of Internal Medicine, College of Oriental Medicine, Kyungwon University) ;
  • Kim Dong-Woo (Department of Internal Medicine, College of Oriental Medicine, Kyungwon University) ;
  • Jun Chan-Yong (Department of Internal Medicine, College of Oriental Medicine, Kyungwon University) ;
  • Park Chong-Hyeong (Department of Internal Medicine, College of Oriental Medicine, Kyungwon University) ;
  • Han Yang-Hee (Department of Internal Medicine, College of Oriental Medicine, Kyungwon University)
  • 전성하 (경원대학교한의과대학 내과학교실) ;
  • 백은기 (경원대학교한의과대학 내과학교실) ;
  • 홍의실 (경원대학교한의과대학 내과학교실) ;
  • 박지윤 (경원대학교한의과대학 내과학교실) ;
  • 한지완 (경원대학교한의과대학 내과학교실) ;
  • 임영남 (경원대학교한의과대학 내과학교실) ;
  • 고호연 (경원대학교한의과대학 내과학교실) ;
  • 김동우 (경원대학교한의과대학 내과학교실) ;
  • 전찬용 (경원대학교한의과대학 내과학교실) ;
  • 박종형 (경원대학교한의과대학 내과학교실) ;
  • 한양희 (경원대학교한의과대학 내과학교실)
  • Published : 2004.12.01
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Abstract

Objective : This study was aimed to evaluate the anti-starvation stress effect of Liriopis Tuber on mice. Method : The first experiment was done to mice which have a high corticosterone level at a short term starvation. The plasma corticosterone level of each mouse was measured over time at 12, 24, 36, 48, 72 hours of starvation respectively. The second experiment was done in the two groups(LT A and LT B) of mice which were in famine for 36.5 hours after being administered Liriopis Tuber three times with different doses(LT A: 1.0 g/.kg and LT B: 3.0g/kg) for three days. The plasma corticosterone levels and rectal temperature were measured when a 36.5-hour of starvation period was finished. Results : 1. The corticosterone level in the mice was significantly increased after a 36.5-hour of starvation. (P<0.001). 2. The plasma corticosterone level was decreased significantly in the group of 3.0g/kg, compared to the control group.(P<0.05) 3. The rectal temperature in the groups of 1.0g/kg and 3.0g/kg were increased slightly in both group. But the two groups didn't show significant change. Conclusion: Based on the above results, Liriopis Tuber might have anti-starvation stress effect and it may be used as anti-starvation stress medicine and anti-stress medicine. Conclusion : Based on the above results, Liriopis Tuber might have anti-starvation stress effect and it may be used as anti-starvation stress medicine and anti-stress medicine.

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