The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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The Effect of Gamigehyuldeung-tang on Hypertension

가미계혈등탕(加味鷄血藤湯)이 고혈압(高血壓)에 미치는 영향(影響)

  • Oh, Young-Seon (Hyehwa Hospital, Daejeon University) ;
  • Kim, Yoon-Sik (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Seol, In-Chan (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Yu, Byeong-Chan (Department of Internal Medicine, College of Oriental Medicine, Daejeon University)
  • 오영선 (대전대학교 혜화병원) ;
  • 김윤식 (대전대학교부속한방병원 내과학교실) ;
  • 설인찬 (대전대학교부속한방병원 내과학교실) ;
  • 유병찬 (대전대학교부속한방병원 내과학교실)
  • Published : 2004.12.30
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Abstract

Objectives : This study was done to investigate the effect of Gamigehyuldeung-tang on hypertension. Methods : After administering Gamigehyuldeung-tang extract to SHR(Spontaneous Hypertensive Rats) for 5 weeks, changes in blood pressure, pulse rate, aldosterone and catecholamine levels in plasma were examined, and immunohistochemical changes and scanning electron microscopic changes were observed. Results : The following results were obtained; blood presure decreased significantly as well as levels of aldosterone, dopamine and epinephrine in SHR. But levels of norepinephrine were unaffected. No capillary vessel dilation was observed. A decrease in cell damage was seen in microscope investigation. Conclusions : These results support a role for Gamigehyuldeung-tang might be usefully applied in treatment of hypertension.

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