Journal of Oriental Neuropsychiatry (동의신경정신과학회지)

The Korean Society of Oriental Neuropsychiatry (대한한방신경정신과학회)
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A study of Gongjin-dan in patients with mild Dementia of Alzheimer type

공진단(供辰丹)이 알츠하이머형 치매 환자에게 미치는 영향

  • Jang, Ha-Jeong (Dept. of Oriental Neuropsychiatry, National Medical Center) ;
  • Sung, Woo-Yong (Dept. of Oriental Neuropsychiatry, National Medical Center) ;
  • Lee, Seung-Hyun (Dept. of Acupuncture and Moxibustion, National Medical Center) ;
  • Son, Ji-Hyung (Dept. of Acupuncture and Moxibustion, National Medical Center) ;
  • Han, Seung-Hea (Dept. of Oriental Internal Medicine, National Medical Center) ;
  • Jung, Hyo-Chang (Dept. of Oriental Neuropsychiatry, National Medical Center)
  • 장하정 (국립의료원 한방신경정신과) ;
  • 성우용 (국립의료원 한방신경정신과) ;
  • 이승현 (국립의료원 침구과) ;
  • 손지형 (국립의료원 침구과) ;
  • 한승혜 (국립의료원 한방내과) ;
  • 정효창 (국립의료원 한방신경정신과)
  • Published : 2004.11.30
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Abstract

Objective : This study is designed to assess the effects of Gongjin-dan on cognitive decline of the patients with mild Dementia of Alzheimer Type(DAT). Method : 33 patients with mild DAT were measured by using K-DRS, and after 100 days again. During 100 days the patients with mild DAT were treated with Gongjin-dan. The scores of K-DRS between before and after treatment were analyzed by paired t-Test. Result : 1. the mean age of patients was $70.3{\pm}4.1$ years (range 65 to 84 years) 2. the mean education of patients was $5.5{\pm}5.3$ years 3. the mean K-DRS score of the patients before treatment was $93.2{\pm}12.1$, and the mean K-DRS score of the patients after treatment was $114.7{\pm}14.5$. K-DRS scores after treatment was significantly different with the K-DRS scores before treatment.(t=9.907, r=.573, p<.00l) Conclusion : Treatment with Gongjin-dan for 100 days increased the cognitive ability in patients with mild DAT

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