Applied Biological Chemistry

The Korean Society for Applied Biological Chemistry (한국응용생명화학회)
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An Antioxidant Homo-Flavoyadorinin-B from Korean Mistletoe (Viscum album var. coloratum)

한국산 겨우살이(Viscum album var. coloratum)로부터 분리한 homo-flavoyadorinin-B의 항산화 활성

  • Choi, Seung-Young (Division of Applied Biology & Chemistry, Kyungpook National University) ;
  • Chung, Shin-Kyo (Department of Food Science & Technology, Kyungpook National University) ;
  • Kim, Suk-Kyung (Department of Food Science & Technology, Kyungpook National University) ;
  • Yoo, Yung-Choon (School of Medicine, Konyang University) ;
  • Lee, Kyung-Bok (School of Medicine, Konyang University) ;
  • Kim, Jong-Bae (Department of Biotechnology & Food Science, Handong University) ;
  • Kim, Ja-Young (Division of Applied Biology & Chemistry, Kyungpook National University) ;
  • Song, Kyung-Sik (Division of Applied Biology & Chemistry, Kyungpook National University)
  • 최승영 (경북대학교 응용생물화학부) ;
  • 정신교 (경북대학교 식품공학과) ;
  • 김숙경 (경북대학교 식품공학과) ;
  • 유영춘 (건양대학교 의과대학) ;
  • 이경복 (건양대학교 의과대학) ;
  • 김종배 (한동대학교 생명 식품공학부) ;
  • 김자영 (경북대학교 응용생물화학부) ;
  • 송경식 (경북대학교 응용생물화학부)
  • Published : 2004.06.30
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Abstract

An antioxidant was isolated from Korean mistletoe (Viscum album var. coloratum) by consecutive purification using silica gel, Sephadex LH-20, and RP-HPLC. The active principle was identified as homo-flavoyadorinin-B (3',7-dimethoxyluteolin-4'-O-[apiosyl $(1{\rightarrow}2)$ glucoside]) by spectral analyses. It inhibited 74.6% of hydroxyl radical and 30.6% of superoxide anion radical at 0.01 mM; however, th~compound did not show any scavenging activity against hydrogen peroxide radical. At 0.1 mM, above compound scavenged superoxide anion radical about twice as effective as positive controls, BHT and ${\alpha}-tocopherol$. Radical scavenging activities of homo-flavoyadorinin-B on DPPH, hydroxyl, and hydrogen peroxide radicals were almost same with those of positive controls.

Keywords

References

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