Journal of Korean Medical Science

Korean Acad Medical Sciences (대한의학회)
권호 표지

Sixteen Cases of Sclerosing Hemangioma of the Lung Including Unusual Presentations

Kim, Gou-Young;Kim, Jhin-Gook;Choi, Yong-Soo;Kim, Ho-Joong;Ahn, Geung-Hwan;Han, Joung-Ho

  • Published : 20040600

⟨ Previous Next ⟩

Abstract

Sclerosing hemangiomas (SH) of the lung are uncommon tumors and are thought to be benign. However, the biologic behavior of this tumor has not yet been characterized adequately. The clinicopathologic features were reviewed and analyzed for 16 cases of SH. The age of the patients ranged from 37 to 73 yr (mean 50.6 yr). There were fifteen female and one male patient. The SH located at the intraparenchyme in 14 cases, the interlobar fissure in one case and the visceral pleura in one case. The size of SH ranged from 0.3 cm to 8 cm (mean 2.6 cm). There were five unusual presentations of SH including a case having two SH with multiple nodules of atypical adenomatous hyperplasia in the same lobe, a case showing adenocarcinomalike area within the SH, a case showing one peribronchial lymph node metastasis (N1 nodal stage) with location of interlobar major fissure, a case showing alveolar adenoma-like area within the SH, and one case with a large visceral pleural-based pedunculated mass presenting as mediastinal mass. All patients were alive and well without recurrence at the last follow up. Here, we reviewed previously published literatures and discussed the histogenesis of SH.

Keywords

References

  1. Cancer v.9 Sclerosing hemangioma (histiocytoma, xanthoma) of the lung Liebow, A.A.;Hubbell, D.S. https://doi.org/10.1002/1097-0142(195601/02)9:1<53::AID-CNCR2820090104>3.0.CO;2-U
  2. Cancer v.58 Sclerosing hemangioma of the lung. Immunohistochemical demonstration of mesenchymal origin using antibodies to tissue-specific intermediate filaments Huszar, M.;Suster, S.;Herczeg, E.;Geiger, B. https://doi.org/10.1002/1097-0142(19861201)58:11<2422::AID-CNCR2820581112>3.0.CO;2-2
  3. Am J Surg Pathol v.7 So-called sclerosing hemangioma of the lung. Evidence for mesothelial origin Katzenstein, A.L.;Weise, D.L.;Fulling, K.;Battifora, H.
  4. Am J Surg Pathol v.21 Neuroendocrine differentiation in 32 cases of so-called sclerosing hemangioma of the lung: identified by immunohistochemical and ultrastructural study Xu, H.M.;Li, W.H.;Hou, N.;Zhang, S.G.;Li, H.F.;Wang, S.Q.;Yu, Z.Y.;Li, Z.J.;Zeng, M.Y.;Zhu, G.M. https://doi.org/10.1097/00000478-199709000-00005
  5. Am J Surg Pathol v.24 Pulmonary sclerosing hemangioma consistently expresses thyroid transcription factor-1 (TTF-1): a new clue to its histogenesis Chan, A.C.;Chan, J.K. https://doi.org/10.1097/00000478-200011000-00009
  6. Am J Surg Pathol v.24 A clinicopathologic study of 100 cases of pulmonary sclerosing hemangioma with immunohistochemical studies: TTF-1 is expressed in both round and surface cells, suggesting an origin from primitive respiratory epithelium Devouassoux-Shisheboran, M.;Hayashi, T.;Linnoila, R.I.;Koss, M.N.;Travis, W.D. https://doi.org/10.1097/00000478-200007000-00002
  7. Histological Typing of Lung Tumors World Health Organization
  8. Histological Typing of Lung and Pleural Tumors Travis, W.D.;Colby, T.V.;Corrin, B.;Brambilla, E.
  9. Am J Surg Pathol v.24 A critical examination of the immunophenotype of pulmonary sclerosing hemangioma Rodriguez-Soto, J.;Colby, T.V.;Rouse, R.V. https://doi.org/10.1097/00000478-200003000-00014
  10. J Histochem Cytochem v.44 Expression of thyroid transcription factor-1 (TTF-1) in fetal and neonatal human lung Stahlman, M.T.;Gray, M.E.;Whitsett, J.A.
  11. Hum Pathol v.30 Utility of surfactant protein B precursor and thyroid transcription factor 1 in differentiating adenocarcinoma of the lung from malignant mesothelioma Khoor, A.;Whitsett, J.A.;Stahlman, M.T.;Olson, S.J.;Cagle, P.T. https://doi.org/10.1016/S0046-8177(99)90096-5
  12. Zhonghua Zhong Liu Za Zhi v.24 Thyroid transcription factor-1 in the histogenesis of plumonary sclerosing hemangioma Lin, D.;Zou, S.;Lu, N.;Liu, X.;Wen, P.;Li, L.
  13. Jpn J Clin Oncol v.16 A case of pneumocytoma (socalled sclerosing hemangioma) with lymph node metastasis Tanaka, I.;Inoue, M.;Matsui, Y.;Oritsu, S.;Akiyama, O.;Takemura, T.;Fujiwara, M.;Kodama, T.;Shimosato, Y.
  14. Histopathology v.10 Sclerosing haemangiomas of the lung Spencer, H.;Nambu, S. https://doi.org/10.1111/j.1365-2559.1986.tb02499.x
  15. Korean J Thorac Cardiovasc Surg v.30 A case of pneumocytoma (sclerosing hemangioma) with lymph node metastasis: a case report Chung, K.Y.;Kim, K.D.,Lim, S.H.;Shin, D.H.
  16. Chin Med J (Engl) v.4 Inflammatory pseudotumor and lung adenoma Chen, C.S.
  17. Histopathology v.41 Unusual sclerosing haemangiomas and sclerosing haemangioma-like lesions, and the value of TTF-1 in making the diagnosis Nicholson. A.G.;Magkou, C.;Snead, D.;Vohra, H.A.;Sheppard, M.N.;Goldstraw, P.;Beddow, E.;Hansell, D.M.;Travis, W.D.;Corrin, B. https://doi.org/10.1046/j.1365-2559.2002.01522.x
  18. Ann Thorac Surg v.73 Sclerosing hemangioma with metastases to multiple nodal stations Yano, M.;Yamakawa, Y.;Kiriyama, M.;Hara, M.;Murase, T. https://doi.org/10.1016/S0003-4975(01)03122-8
  19. Arch Pathol Lab Med v.127 Pulmonary sclerosing hemangioma with lymph node metastases: report of 4 cases Miyagawa-Hayashino, A.;Tazelaar, H.D.;Langel, D.J.;Colby, T.V.
  20. Yonsei Med J v.44 Sclerosing hemangioma with lymph node metastasis Kim, K.H.;Sul, H.J.;Kang, D.Y.
  21. Am J Pathol v.152 Monoclonality of both pale cells and cuboidal cells of sclerosing hemangioma of the lung Niho, S.;Suzuki, K.;Yokose, T.;Kodama, T.;Nishiwaki, Y.;Esumi, H.
  22. Int Surg v.87 Unilateral progressive multiple sclerosing hemangioma in a young female successfully treated by pneumonectomy: report of a case Hayashi, A.;Takamori, S.;Mitsuoka, M.;Fujimoto, K.;Rikimaru, T.;Jimi, A, Shizouzu, K.
  23. Am J Surg Pathol v.4 Sclerosing hemangioma of the lung: a clinicopathologic study of 51 cases Katzenstein, A.L.;Gmelich, J.T.;Carrington, C.B.
  24. Postgrad Med J v.56 Multiple sclerosing haemangiomas of the lung Joshi, K.;Shankar, S.K.;Gopinath, N.;Kumar, R.;Chopra, P.
  25. Am J Surg Pathol v.10 Multiple sclerosing hemangiomas of the lung Noguchi, M.;Kodama, T.;Morinaga, S.;Shimosato, Y.;Saito, T.;Tsuboi, E. https://doi.org/10.1097/00000478-198606000-00008
  26. Nihon Kyobu Shikkan Gakkai Zasshi v.27 [A case of multiple sclerosing hemangiomas of the lung and a review of the literature in Japan] Maezato, K.;Hitomi, S.;Kuwabara, M.
  27. Chest v.101 Bilateral multiple sclerosing hemangiomas of the lung Lee, S.T.;Lee, Y.C.;Hsu, C.Y.;Lin, C.C.
  28. Histopathology v.27 A morphological and immunohistochemical study of 25 cases of so-called sclerosing haemangioma of the lung Leong, A.S.;Chan, K.W.;Seneviratne, H.S. https://doi.org/10.1111/j.1365-2559.1995.tb00020.x
  29. Korean J Thorac Cardiovasc Surg v.32 Multiple sclerosing hemangiomas of the lung -a case report- Chon, S.H.;Jeon, Y.B.;Jung, T.Y.;Chung, W.S.;Kim, Y.H.;Kang, J.H.;Jee, H.O.;Hong, E.K.;Jeon, S.C.
  30. J Comput Assist Tomogr v.18 Sclerosing hemangiomas of the lung and interlobar fissures: CT findings Im, J.G.;Kim, W.H.;Han, M.C.Han, Y.M.;Chung, J.W.;Ahn, J.M.;Do, Y.S.
  31. Ann Thorac Surg v.75 Sclerosing hemangioma isolated to the mediastinum Sakamoto, K.;Okita, M.;Kumagiri, H.;Kawamura, S.;Takeuchi, K.;Mikami, R. https://doi.org/10.1016/S0003-4975(02)04365-5
  32. Pediatr Radiol v.33 Sclerosing haemangioma arising within extralobar pulmonary sequestration Ahmetoglu, A.;Kosucu, P.;Imamoglu, M.;Reis, A.;Cay, A.;Gumele, H.R. https://doi.org/10.1007/s00247-003-0946-1
  33. Virchows Arch v.442 A case of sclerosing hemangioma of the lung presenting as a gigantic tumor occupying the left thoracic cavity Shibata, R.;Mukai, M.;Okada, Y.;Sakamoto, M.;Yamauchi, T.;Kobayashi, K.
  34. Acta Pathol Jpn v.43 Sclerosing hemangioma of the lung: pathological study and enzyme immunoassay for estrogen and progesterone receptors Aihara, T.;Nakajima, T.