Journal of Korean Medicine Rehabilitation (한방재활의학과학회지)

The society of Korean Medicine Rehabilitation (한방재활의학과학회)
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The Effects of KanghwalSokdan-tang(Qianghuoxuduan-tang) in Adjuvant-induced Arthritic Animals

羌活績斷湯이 Adjuvant 誘發 關範 動物 model에 미치는 影響

Kim Geun-Chan;Lee, Myeong-Jong
김근찬;이명종

  • Published : 20040000

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Abstract

Objectives: This study was carried out to examine the effect of KanghwalSokdan-tang(Qianghoxuduan-tang) on anti-inflammatory, analgesic and anti-febrile activities at adjuvant-induced arthritic rats. Methods:KanghwalSokdan-tang(Qianghoxuduan-tang) was administered to rats with Adjuvant-induced arthritis and then the rate of increase of paw edema, WBC, RBC, hemoglobin, ESR, CRP, Protein, albumin, Globulin, GOT. GPT and SOD were measured. Results : 1. It was recognized that KanghwalSokdan-tang(Qianghoxuduan-tang) constrains increment of Paw Edema effectively. 2. It was recognized that KanghwalSokdan-tang(Qianghoxuduan-tang) decreases WBC, ESR, SOD and CRP, Globulin were recognized more effectively. 3. It was recognized that KanghwalSokdan-tang(Qianghoxuduan-tang) increases albumin and Hemoglobin was recognized more effectively. 4. It was recognized that KanghwalSokdan-tang(Qianghoxuduan-tang) has an anti-febrile effect about the febrile of a joint effectively. 5. It was recognized that KanghwalSokdan-tang(Qianghoxuduan-tang) has an analgesic effect about the pain and the increasing Pressure pain threshold of the paws was recognized more effectively. Conclusions: According to the above results, it can be concluded KanghwalSokdan-tang(Qianghoxuduan-tang) showed the treatment effects at adjuvant-induced arthritic rats and on the analgesic effect about the pain at acetic acid-induced mice. It is suggested that it should be studied and developed more throughly for the clinical use.

Keywords

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