Epidemiology and Health

Korean Society of Epidemiology (한국역학회)
권호 표지

Analysis of Transmission Mode of Confirmed Shigellosis in Gyeongju, Korea

경주시에서 발생한 세균성이질 확진자에 대한 유행기전 분석

Jung, Cheoll;Lim, Hyun-Sul;Ha, Gyoung-Yim;Kim, Hee-Su
정철;임현술;하경임;김희수

  • Published : 20040000
⟨ Previous Next ⟩

Abstract

Purpose This study was carried out to investigate the sources of infection and modes ot transmission of an 107 (54males, 53 females) confirmed shigellosis in Gyeongiu from Sept 24 to Oct 24,1998Methods We reviewed hospital recoids of all confirmed shigellosis Thirty-two stiains of Shigella sonnei isolated wereanalyzed m order to trace the source of infections by plasmid profile, antimicrobial drug resistance pattern, biotyping andpulsed-fietd gel electrophoresis (PFGE) Results The first source of infection was estimated to be contaminated underground water and simple piped water caused by leakage from the cess pool Antimicrobial drug resistance pattern showed that all strains were multi-iesistant All isolates had the same XbaI and SfiI PFGE patterns, indicating the epidemiological relationship of the outbreaks strains in this area The majoi charactenstics of diarrhea were watery (84 2%) in nature The climcal symptoms among the diarrheal cases mcluded abdominal pain (86 1%), fever (83 2%), headache (78 2%), ctnll (45 5%) and tenesmus (41 6%) Six cases wereasymptomatic From imtial manifestation to admission were 62$\pm$16 (median 6) days, so it could be transmitted to otheisin this infective period Dmation of admission were 55$\pm$24 (median 6) daysWe can find familial mean secondary attack rate were 38 5%Conclusion it's transmission to othei areas were certified by contaminated water and contact with shigeilosis, andunknown cases were estimated to be transmitted by contacts with inapparent infection By plasmid profile and PFGE, theepidemiological relationship of the outbreaks stiains in this area seemed to be the same micro-organisms

Keywords

References

  1. 서정기 세균성이질 대한의학협회지 1998;35(7)876-83
  2. 최재두 1985년 한국 각지에서 분리한 이질균속의 특성에 관한 연구 대한미생물학회지 1987.22.79-93
  3. 국립보건원. 세균성 이질 감염병 발생정보 1999.10(5).49-55
  4. 장철훈, 송근암, 이복권 세균성 이질의 병인 기전과 최근 유행 양상 대한임상미생물학회지 1999.2.118-24
  5. 국립보건원 국내 세균성 이질 발생 - 1998년 8-10월 감염병 발생정보 1998.9(10).120
  6. 설성용, 김재석, 심행섭, 김정민, 김정완, 이유철, 조동택 한국에서 분리되는 Shlgella sonnei의 분자역학적 분류 대한미생물학회지 1995;30(2):99-113
  7. Matsumoto M, Suzuki Y, Saito M, Ishikawa N,Ohta M Epidemiologic study of Shigella sonnetfrom sequential outbreaks and sporadic cases usingdifferent typing techniques Microbiol Immunol 1998; 42(4) 259-264
  8. 임현술, 정 철, 배근량, 허영주, 이상원, 정은경. 1998년 경주시 한 초등학교 학생과 인근 주민에서 발생한 세균성 이질 예방의학회지 2000.33(1).1-9
  9. Stanley RM, John EC Jr , David F. MicrobialGenetics 2nd ed Boston. Jones and Bartlett, 1994 p116-7
  10. 전도기 이질균 종류 및 우리나라에서의 발생빈도 대한의학지 1970.13.704
  11. Masakado M, Yasumoto S, Makoto S, Naohisa I, Michio O Epidemioloeic study of Shigella sonnetfrom sequential outbreaks and sporadic cases usingdifferent typing techniques Microbial Immunol 1998;42.259-64
  12. Mates A, Eyny D, Philo S. Antimicrobial resistance trends in Shigella serogroups isolated in Israel, 1990-1995 Eur J Clin Microbiol Infect Dis 2000;19.108-11 https://doi.org/10.1007/s100960050439
  13. 설성용, 신행섭. 조동택 Tnmethopnm 내성 Shigella의 분자역학적 분석 대한미생물학회지 1995,30(6).611-26
  14. 설성용, 권영철, 이제철, 이유철, 조동택 Shieella의 비전달성 항균제 내성의 분자유전적 분석 대한미생물학회지 1992,27(2).125-42
  15. 배종면, 이상원, 양병국, 홍성철, 배근량, 강성학. 2000년 상반기 제주도 세균성 이질 역학조사 한국역학회지 2001,23 80-96
  16. 김성한, 전정훈, 김준영, 박미선, 유재연, 강연호, 이복권 국내에서 분리된 Shigella sonnei균에 대한 PFGE를 이용한 Molecular typing 국립보건원보 1999,36.14-21
  17. Newman CP Surveillance and control of Shigella sonnet infection. Commun Dis Rep CDR Rev 1993;3(5).63-8