Anatomy & Biological Anthropology (해부∙생물인류학)

Korean Association of Physical Anthropologists (대한체질인류학회)
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Inhibitary Effect of Rubus coreanus on Compound 48/80-induced Anaphylatic Shock and Vascular Permeability in Vivo

생체실험에서 복분자의 compound 48/80에 의한 아나필락틱 쇽과 혈관 투과성 증가의 억제효과

Li, Guang-Zhao;Chai, Ok-Hee;Song, Chang-Ho
이광소;채옥희;송창호

  • Published : 20040600
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Abstract

As an attempt to search for antiallergic and antiinflammatory activities we examined he potency of Rubus coreanus water extract (RCWE) The effect of RCWE on systemic anaphylactic shock and vascular permeability was investigated Results are 1) compound 48/40-induced mortality rate in mice were significantly inhibited by pretreatment of RCWE and compound 48/40-induced mean death time in mice were delayed by pertreatment of RCWE 2) compound 48/40-induced mesenteric mast cell degranulation in mice were significantly inhibited by pretreatment of RCWE, 3) the increase of vascular permeability induced by compound 48/80 or anti-DNP IgE in rat was significantly inhibited by pretreatment of RCWE These results suggest that RCWE contains substances with an activity to inhibit the systemic anaphylaxis and vascular permeability

Keywords

References

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