Clinical and Experimental Pediatrics

The Korean Pediatric Society (대한소아청소년과학회)
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A Comparison of Clinical Manifestations in Neonates and Infants Infected by Respiratory Syncytial Virus

Respiratory Syncytial Virus에 감염된 신생아와 영아에서 임상 양상에 관한 연구

Lim, In-Suk;Shim, Min-Joo;Kim, Byung-Eui;Chung, Ju-Young;Kim, Chang-Keun;Chey, Myoung-Jae;Kim, Sang-Woo;Kim, Soung-Hee;Han, Tae-Hee
임인숙;심민주;김병의;정주영;김창근;최명재;김상우;김성희;한태희

  • Published : 20040000
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Abstract

Purpose:This study was performed to evaluate of clinical manifestations of neonatal respiratory syncytial virus(RSV) infection, and to evaluate of differences of clinical manifestations between the neonates and infants who were infected by RSV. Methods:We reviewed the medical record of 75 children who were younger than 12 months of age and infected by RSV. We classified then into a neonatal group(n=30) and an infantile group(n=45) and compared the neonatal group with the infantile group by clinical manifestation and chest X-ray. Results:Fever was more significant in the infantile group than the neonatal group(P=0.0256). The chest wall retraction was seen significantly in the neonatal group(P=0.0034). The study didn't show a significant difference in wheezing or rale between the two groups. There was not any significant difference in cyanosis and apnea between the two groups but the symptoms appeared more frequently in the neonatal group. With regard to chest X-rays, pneumonia is seen more frequently in the neonatal group(23/30, 76.67%) and bronchiolitis is seen more frequently in the infantile group (25/45, 55.55%). Conclusion:Neonatal RSV infections appear with fever less than infantile RSV infection and may appear with mild clinical manifestations, but chest retraction and pneumonia are more frequently present than in the infantile group. Therefores, neonate needs careful observation and treatment. (Korean J Pediatr 2004;47:949-952)

Keywords

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