BF-7 Improved Memory Function and Protected Neuron from Oxidative Stress

BF-7의 기억력 향상효과 및 산화적 스트레스로 인한 신경손상의 억제효과

Lee, Moo-Yeol;Lee, Sang-Hyung;Lee, Jung-Sang;Min, Kyung-Joon;Lee, Kwang-Gill;Yeo, Joo-Hong;Kwon, Hye-Jin;Lee, Jeong-Kyu;Kang, Yong-Koo;Lee, Do-Yeon;Chung, Yoon-Hee;Kim, Kyung-Yong;Kim, Sung-Su;Lee, Won-Bok
이무열;이상형;이정상;민경준;이광길;여주홍;권혜진;이정규;강용구;이도연;정윤희;김경용;김성수;이원복

  • Published : 20041200

Abstract

Endogenously or exogenously generated oxidative stress impair organs, especially brain. Also, the oxidative stress appears to be a negative factor on normal brain function, like memory and cognition. Our result showed that BF-7, extracted from Bombyx mori, effectively diminished oxidative stress, leading to the protection of neuron from reactive oxygen species donated by $FeSO_4$. Clinical experiments showed that BF-7 significantly improved memory and cognitive functions of normal adults in a dose-dependent manner. Thus, our results suggest that BF-7 play a role in the improvement of brain functions by removing oxidative stress, and provide therapeutic potential role of BF-7 to protect nervous system from oxidative damag.

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References

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