Journal of Nutrition and Health

The Korean Nutrition Society (한국영양학회)
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Effects of Acorn Supplementation on Lipid Profiles and Antioxidant Enzyme Activities in High Fat Diet-Induced Obese Rats

고지방 식이로 유도된 비만흰쥐의 체내 지질패턴 및 항산화효소 활성에 도토리 급여의 효과

  • 강명화 (호서대학교 자연과학부 식품영양전공) ;
  • 이지현 (호서대학교 자연과학부 식품영양전) ;
  • 이정숙 (한국식품영양재) ;
  • 김주현 (한국식품영양재) ;
  • 정혜경 (호서대학교 자연과학부 식품영양전공)
  • Published : 2004.04.01
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Abstract

This study was performed to investigate the effect of acorn supplementation on the lipid profile and redox antioxidant enzyme activities in obese rat. Obesity in the rats was induced by feeding diet contained 10％ lard and 0.5％ cholesterol for 4 week. After 4 weeks, rats were divided into the following 5 groups; high fat diet (Control), high fat diet plus 10％ Acorn powder (APlO％), high fat diet plus 20％ Acorn powder (AP20％), high fat diet plus 0.2％ Acorn extract (AE0.2％), high fat diet plus 0.5％ Acorn extract (AE0.5％). Total food intake and food efficiency ratio (FER) was not significantly different by acorn powder and extract supplementation. But, body weight was decreased by 20％ acorn powder. Acorn powder and extract supplementation for 4 weeks tend to decrease total cholesterol and triglyceride level on the serum and hepatic tissue. There was no significant difference in hepatic glutathione (GSH) content among all the groups. The hepatic GST activity in acorn supplemented groups was lower than that of control. Glutathione peroxidase and catalase activities were higher in acorn supplemented groups than that of control. Hepatic TBARS levels of experimental groups were also significantly lower than that of control group. Our finding suggest that acorn powders and extract might have potential role for improving lipid profiles and antioxidant enzyme activities in obese rats.

Keywords

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