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The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
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Investigation of Antidiabetic Medicinal Plants using an Oriental Medicinal Database

동양의학 데이터베이스를 이용한 당뇨병에 효능을 가진 생약재의 탐색

  • Kim, Dong-Hyun (Department of Innovative Industrial Technology, Graduate School of Venture, Hoseo University) ;
  • Kang, Young-Gu (Department of Innovative Industrial Technology, Graduate School of Venture, Hoseo University) ;
  • Kim, Hong (Department of Innovative Industrial Technology, Graduate School of Venture, Hoseo University) ;
  • Chae, Hee-Jung (Department of Food and Biotechnology, Hoseo University)
  • 김동현 (호서대학교 벤처전문대학원) ;
  • 강영구 (호서대학교 벤처전문대학원) ;
  • 김홍 (호서대학교 벤처전문대학원) ;
  • 채희정 (호서대학교 식품생물공학전공)
  • Published : 2004.04.01
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Abstract

Various medicinal plants were examined as resources for antidiabetic biomaterials, using an oriental medicinal database. The prescription frequency and dosage of medicinal plants in 131 antidiabetic prescriptions were analyzed. Total prescription score of each medical plant was summed up from prescription table and score table. High-scored medicinal plants have been widely studied in the previous research on the diabetic treatment. Consequently, dangui, hwangryun, maekmoondong, ginseng, chick, saengjihwang, omija, bokryung, Jimo and cheonhwaboon were assumed to have high antidiabetic activities.

당뇨병에 효능을 보이는 생리활성소재의 탐색원을 발굴하기 위한 방법의 하나로 동양의학 데이터베이스의 처방정보를 활용 하였다. 신동의약보감에 포함되어 있는 131건의 당뇨병 처방천연 약재의 처방 빈도와 처방분량을 분석하였다. 처방 순위와 처방 분량에 따라 마련된 점수표 (score table)를 기준으로 총 처방점수 (total prescription score)를 작성하였다. 선행 연구 결과들을 조사 한 결과 총 처방점수가 높은 약재들을 소재로 한 관련 보고들이 많은 것으로 나타났다. 결과적으로 당귀, 황련, 맥문동, 인삼, 칡, 생지황, 오미자, 복령, 지모, 천화분 등이 당뇨병에 효과가 있으며 이들 약재를 이용한 항당뇨 소재의 탐색 방법 이 제안되었다.

Keywords

References

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