Journal of Microbiology and Biotechnology

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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Identification of Streptomyces sp. Producing Antibiotics Against Phytopathogenic Fungi, and Its Structure

  • Kim, Jung-Han (Department af Biotechnology and Bioproducts Research Center, Yonsei University) ;
  • Jeong, Do-Hyeon (Department af Biotechnology and Bioproducts Research Center, Yonsei University) ;
  • Park, Ki-Duk (Department af Biotechnology and Bioproducts Research Center, Yonsei University) ;
  • Kim, Sung-Han (Department af Biotechnology and Bioproducts Research Center, Yonsei University) ;
  • Kim, Kyung-Rae (Department af Pharmacy, Sunggunkwan University) ;
  • Choi, Sung-Won (R&D Center Greenbiatech Ca., Ltd.) ;
  • Kim, Ji-Tae (R&D Center Greenbiatech Ca., Ltd.) ;
  • Choi, Ki-Hyun (R&D Center Greenbiatech Ca., Ltd.)
  • Published : 2004.02.01
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Abstract

In order to develop a biocontrol agent that can effectively control Fusarium wilt on Cymbidium genus, the effectiveness of antagonistic microbes against the cause pathogen was screened. The selected microbe showed a broad spectrum of antifungal activity, and the culture broth of this microbe had better preventive effect on Fusarium wilt than the commercial chemical agent in the pot assay. This isolated strain, GBA-12, was identified as Streptomyces kasugaensis, and the antifungal substance was purified from a broth culture of GBA-12. This purified substance was identified as a polyene macrolide (YS-822A) that was newly discovered from Streptomyces kasugaensis, and it exhibited antifungal activity against several phytopathogenic fungi.

Keywords

References

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