Entomological Research

The Entomological Society of Korea (한국곤충학회)
권호 표지

Immune-Enhancing Activity Screening on Extracts from Two Crickets, Gryllus bimaculatus and Teleogryllus emma

  • Seo, Dong-Hwan (Dept. of Biology, Institute, of Traditional Medicine and Bioscience, Daejeon University) ;
  • Hwang, Seock-Yeon (Dept. of Clinical Laboratory Medicine, Chungbuk National University Hospital) ;
  • Han, Jikhyon (Dept. of Biology, Institute, of Traditional Medicine and Bioscience, Daejeon University) ;
  • Koh, Sang-Kyun (Dept. of Microbiology, Daejeon University) ;
  • Kim, Iksoo (Dept. of Sericulture and Entomology, National Institute of Agicultural Science and Technology) ;
  • Ryu, Kang Sun (Dept. of Sericulture and Entomology, National Institute of Agricultural Science and Technology) ;
  • Yun, Chi-Young (Dept. of Biology, Institute, of Traditional Medicine and Bioscience, Daejeon University)
  • Published : 2004.09.01
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Abstract

This study was performed to explore novel and valuable uses of insect resources, important subjects of the natural compound used in bio-industries. The whole bodies of two crickets, Grylius bimaculatus and Teleogryllus emma, selected from medicinal insect species, were carefully ground and treated with 80% EtOH. The insect extracts were solubilized and separated by hexane, butanol, and D.W according to their pola,rities. Three types of extracts, a D.W fraction (G1) and a boiling extract (G2) of an introduced cricket, G. bimaculatus, and a D.W fraction (Tl) of a Korean local cricket, T. emma, were prepared to assay immune stimulating activity of cricket originated compounds. The all of three treated cricket extracts showed to increase IL-4, IFN -${\gamma}$, and TNF-$\alpha$. Among those extract, extract G2, boiled extract from G. bimaculatus, was the best immune-enhancing fraction. The results of this study could be fundamental information for further works to use insects as natural resources having plenty of potentials and varieties.

Keywords

References

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