Journal of Sensor Science and Technology (센서학회지)

The Korean Sensors Society (한국센서학회)
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Microbead-based bio-assay using quantum dot fluorescence in a microfluidic chip

미소유체 칩 상에서 Quantum Dot 및 마이크로 비드를 이용한 생체물질 분석

  • Yun, Kwang-Seok (Department of Electrical Engineering and Computer Science (Division of Electrical Engineering))) ;
  • Lee, Do-Hoon (Department of Biological Science, Korea Advanced Institute of Science and Technology (KAIST))) ;
  • Kim, Hak-Sung (Department of Biological Science, Korea Advanced Institute of Science and Technology (KAIST))) ;
  • Yoon, Eui-Sik (Department of Electrical Engineering and Computer Science (Division of Electrical Engineering)))
  • 윤광석 (한국과학기술원 전자전산학과(전기 및 전자공학)) ;
  • 이도훈 (한국과학기술원 생명과학과) ;
  • 김학성 (한국과학기술원 생명과학과) ;
  • 윤의식 (한국과학기술원 전자전산학과(전기 및 전자공학))
  • Published : 2005.09.30
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Abstract

We present a microfluidic chip designed for the detection of antibody by using quantum dots fluorescence and a microbead-based assay. A custom designed PDMS microfluidic chip with multi-layer channel is utilized for capturing microbeads; antibody injection into each micro-well; QD injection; and fluorescence detection. The experiment using the fabricated microfluidic chip has been performed on solutions with various concentrations of antibody and has shown correlated fluorescent intensities.

Keywords

References

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