Parasites, Hosts and Diseases

The Korea Society for Parasitology and Tropical Medicine (대한기생충학·열대의학회)
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Seroprevalence of toxoplasmosis in Korean pregnant women

  • SONG Kyoung-Ju (Department of Microbiology, Ajou University School of Medicine) ;
  • SHIN Jong-Chul (Department of Obstetrics and Gynecology, Catholic University of Korea College of Medicine) ;
  • SHIN Ho-Joon (Department of Microbiology, Ajou University School of Medicine) ;
  • NAM Ho-Woo (Department of Parasitology and Catholic Institute of Parasitic Diseases, Catholic University of Korea College of Medicine)
  • Published : 2005.06.01
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Abstract

This study was performed in order to evaluate the sero-epidemiological status of toxoplasmosis in pregnant Korean women. Among 5,175 sera and 750 amniotic fluid samples obtained from pregnant women, 41 serum samples $(0.79\%)\;and\;10 (1.33\%)$ amniotic fluid samples tested positive for IgG antibodies by ELISA. Fifty one cases showing a score more than 0.25 on ELISA were tested for PCR reaction against the SAG1 gene. Only one case of the 51 ELISA positive cases exhibited a positive reaction on all tests. This case had a history of acute nephropyelitis during early pregnancy, but fortunately, had delivered a phenotypically healthy baby. In this study, the seroprevalence of toxoplasmosis in pregnant women was found to be comparatively low, consistent with previous reports from Korea. However our trials, performed with a variety of diagnostic tools, were considered to be useful for the precise diagnosis of congenital toxoplasmosis.

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References

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