The Korea Journal of Herbology (대한본초학회지)
- Volume 20 Issue 2
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- Pages.69-75
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- 2005
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- 1229-1765(pISSN)
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- 2288-7199(eISSN)
Effects of Gamibangpungtongseungsan on lipid composition and antioxidant in rat fed high fat
가미방풍통성산(加味防風通聖散)이 고지방식이 급여 흰쥐의 체지질구성과 항산화능에 미치는 영향
- Lee, Jang-Cheon (Dept. of Oriental Medicine, Sangji university)
- 이장천 (상지대학교 한의과대학)
- Published : 2005.06.30
Abstract
Objective : Effects of Gamibangpungtongseungsan on lipid composition and antioxidant system were investigated in rat fed high fat diet. Methods : We fed control group rats high fat diet and administered normal saline for 8 weeks, and experimental group rats high fat diet and administered extract of Gamibangpungtongseungsan for 8 weeks. Results : Body weight gain, concentration of plasma triglyceride, total cholesterol, LDL-cholesterol showed a tendency to decrease in Gamibangpungtongseungsan groups. However, the concentration of LDL-cholesterol showed a tendency to increase in Gamibangpungtongseungsan groups. Plasma and liver TBARS concentration showed a low values in Gamibangpungtongseungsan groups. Activities of SOD, GSH-Px and CAT showed a tendency to increase in Gamibangpungtongseungsan groups. Conclusions : These results indicate that Gamibangpungtongseungsan has a deep inhibitory effect on lipid composition and antioxidant system.