The Korea Journal of Herbology (대한본초학회지)

The Korea Association of Herbology (대한본초학회)
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A Study on Physiological Activities of Coptidis Rhizoma and Application for Cosmetic Ingredients

황련(黃連)의 생리활성검증 및 화장품 소재로서의 이용 가능성

  • Lee, Jin-Tae (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Lee, Chang-Eon (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Kim, Jun-Hong (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Son, Jun-Ho (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Kwak, Jae-Hoon (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Lee, Jin-Young (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Park, Tae-Soon (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Bae, Ho-Jung (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Jang, Min-Jung (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Jo, Cheol-Hun (Advanced Radiation Technology Institute) ;
  • An, Bong-Jeun (Dept. of Cosmeceutical Science, Daegu Haany University)
  • 이진태 (대구한의대학교 화장품약리학과) ;
  • 이창언 (대구한의대학교 화장품약리학과) ;
  • 김준홍 (대구한의대학교 화장품약리학과) ;
  • 손준호 (대구한의대학교 화장품약리학과) ;
  • 곽재훈 (대구한의대학교 화장품약리학과) ;
  • 이진영 (대구한의대학교 화장품약리학과) ;
  • 박태순 (대구한의대학교 화장품약리학과) ;
  • 배호정 (대구한의대학교 화장품약리학과) ;
  • 장민정 (대구한의대학교 화장품약리학과) ;
  • 조철훈 (한국원자력연구소 방사선연구원) ;
  • 안봉전 (대구한의대학교 화장품약리학과)
  • Published : 2005.09.30
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Abstract

Objectives : The physiological activities of Coptidis Rhizoma investigated for application as a cosmetic ingredients. Methods : We were experimented anti-oxidation effect, growth inhibition ability on cancer cells, antibacterial activity on various kinds of bacteria of skin. Results : The results were obtained as follows : Electron-donating ability(EDA) shows that Coptidis Rhizoma extracted with ethanol(94.51%) gives higher EDA in comparison to that extracted with water in 1000 ppm(63.24%). In the test of SOD-like activity, ethanol extract showed quite more activity with 81.01% in 1000 ppm, while water extract was low in 18.22%. In the inhibition activity of Xathine oxidase, ethanol extract showed higher inhibition activity compared to water extract. In measuring lipid oxidation inhibition ability using fish oil, ethanol extract in 100 ppm showed prominent ability. In the oxidation inhibition effect added with $Cu^{2+}\;ion\;and\;Fe^{2+}$ ion as a oxidation promoter, ethanol extract in 1000 ppm, each in the proportion of 90% and 92%, showed high oxidation inhibition effect compared with water extract. Conclusions : The results indicated that, ethanol extract which is superior in its anti-oxidation and antibacterial effect is useful to be applied in cosmetic industry.

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