The Korea Journal of Herbology (대한본초학회지)

The Korea Association of Herbology (대한본초학회)
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Antioxidant, Anticancer and Antibacterial Activities of Naesohwangryntang and its Ingredients

내소황련탕(內疎黃連湯) 및 구성약재의 항산화효과 검증과 항암 및 항균효과

  • Lee, Chang-Eon (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Son, Jun-Ho (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Lee, Jin-Young (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Park, Tae-Soon (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Park, Jung-Mi (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Bae, Ho-Jung (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Pyeon, Jeong-Ran (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • An, Bong-Jeun (Dept. of Cosmeceutical Science, Daegu Haany University)
  • 이창언 (대구한의대학교 화장품약리학과) ;
  • 손준호 (대구한의대학교 화장품약리학과) ;
  • 이진영 (대구한의대학교 화장품약리학과) ;
  • 박태순 (대구한의대학교 화장품약리학과) ;
  • 박정미 (대구한의대학교 화장품약리학과) ;
  • 배호정 (대구한의대학교 화장품약리학과) ;
  • 편정란 (대구한의대학교 화장품약리학과) ;
  • 안봉전 (대구한의대학교 화장품약리학과)
  • Published : 2005.12.30
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Abstract

Objectives : Antioxidant, Anticancer and Antibacterial Activities of Naesohwangryntang and its composition oriental medicines. Methods : We were experimented anti-oxidation effect and growth inhibition ability on cancer cells and antibacterial activity on various kinds of bacteria of skin. Results : The results were obtained as follows : Electron donating ability(EDA) of water extract Naesohwangryntang and ethanol extract Naesohwangryntang was 60% and 70% at 1000 ppm concentration. In the test of SOD-like activity, ethanol extract showed more activity with 27.4% in 700 ppm, while water extract was low in 19.6%. Clear zones formed by sample against the human skin-resident microflora indicated that anti-microbial activity of ethanol extract Naesohwangryntang was higher than that of water extract Naesohwangryntang. The growth inhibition rates of each sample on lung-cancer(A549), at 1000 ppm cancer cell was over 40%. The growth inhibition rate of the each sample melanoma-cancer(B16F10, G361), at 1000 ppm was over 80%. Conclusions : The results indicated that, ethanol extract which is superior in its anti-oxidation and antibacterial effect is useful to be applied in cosmetic industry.

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