The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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The Effect of Yookmijihwang-tang(Yookmijihwang-tang:YJT) on Mice with Diabetic Nephropathy Induced by Alloxan

육미지황탕(六味地黃湯)이 Alloxan으로 유발(誘發)된 생쥐의 당뇨병성(糖尿病性) 신증(腎症)에 미치는 영향(影響)

  • Kim, Yong-Sung (Dept. of Internal Medicine, Collage of Oriental Medicine, Dong-Shin University) ;
  • Seo, Soo-Hwan (Dept. of Internal Medicine, Collage of Oriental Medicine, Dong-Shin University)
  • 김용성 (동신대학교 한의과대학 내과학교실) ;
  • 서수환 (동신대학교 한의과대학 내과학교실)
  • Published : 2005.12.30
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Abstract

This study was done to investigate recovery effects of YJT, which has been used clinically in diabetes therapy. Mice were administerd Alloxan to induce diabetes. There body weight and kidney weight changes, BUN, creatinine, glucose, total protein and ALP activity in serum, urinalysis, excretion volume of Na+, K+ in urine were measured. The results were as follows: 1. Increase in body weight and kidney weight and the ratio of kidney to body weight of YJT treated group showed similar results with those of normal group. 2 The BUN, creatinine, ALP activity levels in serum of YJT treated group were similar with those of normal group. 3. The glucose level in serum of YJT treated group was better than that of control group 4. The result of the urinalysis in the group of YJT was almost same as that of control group The above results suggest that YJT partially improves the function of the kidney.

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