The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology (한방안이비인후피부과학회지)

The Society of Korean Medicine Ophthalmology, Otolaryngology & Dermatology (대한한방안이비인후피부과학회)
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Effects of Cytotoxic and Antioxidant of Methanol Extracts from Medicinal Plants

어성초 돌콩 추출물의 항암활성 및 항산화 활성 효과

  • Lee, Jeong-Ho (Dept. of Oriental Pharmacy, College of Pharmacy Wonkwang University) ;
  • Kim, Yun-Gyoung (Dept. of Oriental Pharmacy, College of Pharmacy Wonkwang University) ;
  • Choi, Choi-Mun (Dept. of Herbology, College of Oriental Medicine, Woosuk University)
  • 이정호 (원광대학교 약학대학 한약학과) ;
  • 김윤경 (원광대학교 약학대학 한약학과) ;
  • 최문일 (우석대학교 한의과대학 본초학교실)
  • Published : 2005.12.25
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Abstract

This study was performed to determine the cytotoxic effect of methanol extract from Houttuynia Cordata and Glycine soja. The cell viability was determined by MTT method. Their cytotoxic activities against three cancer cell lines such as A549, MDA-MB-231 and SNU-C4 cell line were tested. Among them, The methanol extract of Houttuynia Cordata showed the strongest cytotoxic effect against SNU-C4 cells. These results suggest that the methanol extract of Houttuynia Cordata possessed a potential antitumorous agent. The free radical scavenging activity using DPPH method was the strongest of Houttuynia Cordata methanol extract and ethyl acetate fraction.

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