Effect of Dietary Supplementation of Terrapin or Snake Extract on Exercise Performance in Rats

용봉탕 또는 사탕(蛇湯) 보충식이가 횐쥐의 지구력 운동 수행능력에 미치는 영향

  • Published : 2005.04.30

Abstract

Effect of terrapin or snake extract on forced-swimming capacity and related biochemical parameters of SD rats was evaluated. Treatment groups were fed diet supplemented with 5% terrapin extract or 1% snake extract for 4 weeks. After adaptation for 1 week, each group was divided into two subgroups: one group swam for 90 min (90-min subgroups), and the other swam until exhaustion (all-out subgroups). No significant difference was observed in swimming time until exhaustion among the groups. After swimming for 90 min, contents of fatigue factors of serum such as lactate, inorganic phosphate, creatine kinase, and ammonia were not significantly different (p < 0.05) between control and treatment groups, including all-out subgroups, except for lactate concentration. These results indicated that terrapin or snake extract had little effect on forced-swimming capacity of rats.

구전에 의해서 건강 보신식품으로 알려져 온 뱀과 자라에 대하여 이들 추출물에 대하여 흰쥐의 운동수행능력에 미치는 영향에 대하여 평가하고, 보신식품에 대한 기초자료 축적 및 향후 의약품 대체식품 개발에 이용 가능한 원료로서의 가능성을 평가하고자 하였다. 흰쥐의 식이에 5% 사탕 또는 1% 용봉탕을 첨가하고 4주간 사육한 후 90분간 수영시킨 군(90-min subgroups)과 탈진 때까지 수영시킨 군(all-out subgroups)을 두 하부군으로 나누어 분석하였다. 강제수영능력 시간을 측정한 결과 용봉탕 또는 사탕은 흰쥐의 수영시간에 거의 영향을 미치지 않는 것으로 나타났다. 90-min subgroups의 피로요소 측정 결과 대조군에 비해 사탕 추출물 첨가식이를 섭취한 군의 혈청 젖산 농도가 유의적으로 낮았으나(p<0.05), 무기인산, creatine kinase 및 요산 농도는 ET군과 ES군 모두 대조군과의 유의적인 차이는 없었다. All-out subgroups과 대조군의 혈청 피로 요소 역시 사탕 섭취군의 젖산 농도가 높았던 점 이외에 다른 요소의 농도는 유의적인 차이가 없었다. 따라서, 용봉탕 및 사창 추출물의 섭취로 인한 지구력운동 수행에 대한 효능 및 혈청 피로 요소에 미치는 영향은 전혀 없다고 판단할 수 있으며, 이들이 몸을 이롭게 한다는 인식은 영양 보충식품으로 이해할 수는 있지만, 건강기능 면에서는 잘못된 믿음이라고 판단된다.

Keywords

References

  1. You SY, Kim HK. Food habits and health food consumption patterns of adults in the Ulsan area. Korean J. Community Nutr. 8: 889-900 (2003)
  2. NamKung S. A study on the recognition for health food of residents in Seoul area. J. East. Asian Soc. Diet. Life 11: 446-454 (2001)
  3. Koo NS, Park JY. Consumption pattern of health food by adults in Taejon. Korean J. Community Nutr. 5: 452-460 (2000)
  4. Pack HA. Evidence based dietary supplements for fatigue and sexual function. J. Korean Acad. Fam. Med. 24: 786-799 (2003)
  5. Kang IH. Health Food of Korean. Daehan Printing and Publishing Co., Ltd., Seoul, Korea. p. 26 (1992)
  6. Lee JH. Dongeuibogam, Samsung Munhwasa Publishing, Co., Seoul, Korea. p. 89 (1991)
  7. KFDA. Food Code, Korea Foods Industry Association Publishing, Moonyongsa Co., Seoul, Korea. pp. 469-507, 825 (2004)
  8. Matsumoto K, Ishihara K, Tanaka K, Inoue K, Fushiki T. An adjustable-current swimming pool for the evaluation of endurance capacity of mice. J. Appl. Physiol. 81: 1843-1849 (1996) https://doi.org/10.1152/jappl.1996.81.4.1843
  9. Ravi Kiran T, Subramanyam MV, Asha Devi S. Swim exercise training and adaptations in the antioxidant defense system of myocardium of old rats: relationship to swim intensity and duration. Comp. Biochem. Physiol. Part B 137: 187-196 (2004) https://doi.org/10.1016/j.cbpc.2003.11.002
  10. Devi SA, Jolitha AB, Prathima S. Temperature-induced changes in anaerobic capacity of interventricular septum in trained young and middle-aged rats. Biogerontology 3: 155-160 (2002) https://doi.org/10.1023/A:1015634906540
  11. Chun Y, Yin ZD. Glycogen assay for diagnosis of female genital chlamydia trachomatis infection. J. Clin. Microbiol. 36: 1981-1982 (1998)
  12. Pesce A, Mckay RH, Stolzenbach F, Ccahn RD, Kaplan NO. Comparative enzymology of LDH. J. BioI. Chem. 239: 1753-1761 (1964)
  13. Srere PA. Citrate synthase. Method. Enzymol. 13: 3-11 (1969) https://doi.org/10.1016/0076-6879(69)13005-0
  14. Meneguello MO, Mendoca JR., Lancha Jr. AH, Costa Rosa LFBP. Effect of arginine, ornithine and citrulline supplementation upon performance and metabolism of trained rats. Cell. Biochem. Func. 21: 85-91 (2003) https://doi.org/10.1002/cbf.1000
  15. Vamier M, Leese GP, Thompson J, Rennie MJ. Stimulatory effect of glutamine on glycogen accumulation in human skeletal muscle. Am. J. Physiol. 269: E309-E315 (1995)
  16. Maclaren DP, Gibson H, Parry-Billings M, Edwards RH. A review of metabolism and physiological factors in fatigue. Exerc. Sport Sci. Rev. 17: 29-66 (1989)
  17. Hickson RC, Rennie MJ, Conlee RK, Winder WW, Holloszy JO. Effects of increased plasma fatty acids on glycogen utilization and endurance. J. Appl. Physiol. 43: R829-R833 (1977) https://doi.org/10.1152/jappl.1977.43.5.829
  18. Ryu SP, lang UC, Lee SJ, Kwon TD, lung KU, Lee SC. Glucose administration on energy substrates utilization during exercise. J. Nutr. Sci. 4: 49-60 (2000)
  19. Sachan OS, Hongu N. Increases in VO2max and metabolic markers of fat oxidation by caffeine, camitine, and choline supplementation in rats. J. Nutr. Biochem. 11: 521-526 (2000) https://doi.org/10.1016/S0955-2863(00)00119-4
  20. Messonnier L, Freund H, Feasson L, Prieur F, Castells J, Denis C, Linossier MT, Geyssant A, Lacour JR. Blood lactate exchange and removal abilities after relative high-intensity exercise: effects of training in normoxia and hypoxia. Eur. J. Appl. Physiol, 84: 403-412 (2001) https://doi.org/10.1007/s004210000378
  21. Wallimann T, Wyss M, Brdiczka D, Nicolay K, Eppenberger HK. Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the 'phosphocreatine circuit' for cellular energy homeostasis. Biochem. J. 281: 21-40 (1992) https://doi.org/10.1042/bj2810021
  22. Kim SJ, Back YH, Yeom WS. The change of blood lactate concentration, LDH, CPK, electrolytes, immune system under vitamin B complex and C intake of high school basketball players. J. Nutr. Sci. 4: 61-70 (2000)
  23. James LG, Sareen SG. Advanced Nutrition and Human Metabolism. 3rd ed. Wadsworth/Thomson Learning Press, Belmont, CA, USA. pp. 220-244 (1999)
  24. Mosso A, Charles C. Fatigue. Thomas Publishers. Rome, Italy (1997)
  25. Mutch BJC, Banister EW. Ammonia metabolism in exercise and fatigue: a review. Med. Sci. Sports Exerc. 15: 41-50 (1983)
  26. Jones NL. Muscle performance and fatigue: overview. Hypoxia, Exercise, and Altitude: Proceedings of the third Banff international hypoxia symposium, Alberta, Canada. pp. 237-242 (1983)