Journal of the East Asian Society of Dietary Life (동아시아식생활학회지)

The East Asian Society of Dietary Life (동아시아식생활학회)
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Effect of Beni-Koji with Chitosan-Ascorbate on Serum Lipid Profile of Rats Fed a High Fat Diet

Chitosan-Ascorbate 함유 홍국이 고지방 식이 흰쥐의 혈청지질에 미치는 영향

  • Shin Jin-Gi (Dept. of Food Science and Technology, Kyungpook National University) ;
  • Lee Sang-Il (Dept. of Food Nutrition and Cookery, Keimyung College) ;
  • Kwon Jung-Ho (Dept. of Food Science and Technology, Kyungpook National University) ;
  • Kim Soon-Dong (Dept. of Food Science and Technology, Food Industrial Technology, Catholic University of Daegu)
  • 신진기 (경북대학교 식품공학과) ;
  • 이상일 (계명문화대학 식품영양조리과) ;
  • 권중호 (경북대학교 식품공학과) ;
  • 김순동 (대구가톨릭대학교 식품산업학부 식품공학)
  • Published : 2005.10.01
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Abstract

Dietary effect of soyfiber beni-koji (SBK) with chitosan-ascorbate (CA) on the level of serum lipids in rats fed a high fat diet was investigated The experimental groups which were divided into high fat diet control group(HC-group), $2\%\;SBK+0.1\%$ CA mixture diet group(CA1-group), $2\%\;SBK+0.15\%$ CA mixture diet group(CA2-group), and $2\%\;SBK+0.2\%$ CA mixture diet group (CA2-group) were fed for 4 weeks. Weight gains in CA2- and CA3-group were $5.3\%\;and\;9.5\%$ lower than that of HC-group, respectively, while there was no significant difference in feed intakes, feed efficiency ratio and organs weight Level of serum triglyceride in $C_3-group\;was\;21\%$ lower than that of HC-group. Level of serum total cholesterol and LDL-cholesterol in CA2- and CA3-group were $22.1\~22.7\%\;and\;58.6\~64.3\%$ lower than those of HC-group, respectively. Atherogenic index decreased with the higher level of CA. Level of lipid peroxide in CA3-group was $24\%$ lower than that of HC-group, while there was no significant difference in GSH(Glutathione-S-transferase) content O type activities of XOD(xanthine oxidase) in the treated groups were lower, especially the activity in CA3-group was $51.6\%$ lower than that of HC-group. Also, O/T ratio of XOD was lower, showing $21.7\~23.5\%$ in treated groups and $34.0\%$ in HC-group(p<0.05). GST activities were 332.52 units in HC-group and $350.28\~355.63$ units in the treated groups, but there were no significant differences among them.

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