Stability and Rheology of Cream Containing Sopoongsan

소풍산을 첨가한 크림의 안정성 및 물성 변화

  • An, Bong-Jeun (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Lee, Jin-Young (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Lee, Chang-Eon (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Son, Jun-Ho (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Park, Jung-Mi (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Park, Tae-Soon (Department of Cosmeceutical Science, Daegu Haany University)
  • 안봉전 (대구한의대학교 화장품약리학과) ;
  • 이진영 (대구한의대학교 화장품약리학과) ;
  • 이창언 (대구한의대학교 화장품약리학과) ;
  • 손준호 (대구한의대학교 화장품약리학과) ;
  • 박정미 (대구한의대학교 화장품약리학과) ;
  • 박태순 (대구한의대학교 화장품약리학과)
  • Published : 2005.12.31

Abstract

Sopoongsan is an oriental medicinal composition including 12 medicinal herbs. Sopoongsan is known to have anti-inflammatory, antimicrobial, anti-allergic, and anticancer effects on human skin. The results of stability test showed that the creams containing Sopoongsan extracts were very stable at both accelerated temperature conditions and sun-light. And pH and viscosity of each cream did not change greatly for 56 days. From the particle size and rheological measurements, it can be known that when the amount of the Sopoongsan extracts increases, the mean value of particle size decreases, and the value of the complex modulus and loss angle increases, which means the Sopoongsan extracts help stabilize the emulsion. From the result of human patch test to assess the safety of cream containing Sopoongsan extracts, there was no stimulus of negative reaction on skin. In result of the user tests, it can be known that the higher concentration of the Sopoongsan was preferred by customers.

Keywords

References

  1. Heo, J. (1994) <>, Yeo-Gang Republic, 57. Korea
  2. Gilchrest, B. A. (1989) Skin aging and photoaging: an overview. J. Am. Acad. Dermatol. 21, 610-613 https://doi.org/10.1016/S0190-9622(89)70227-9
  3. Bernstein, E. F., Chen, Y. Q,, Tamai, K, Shepley, K. J., Resnik, K. S., Zhang, R., Tuan, R., Mauviel, A. and Uitto, J. (1994) Enhanced elastin and fibrillin gene expression in chronically photodamaged skin. J. Invest. Dermatol. 103, 182-186 https://doi.org/10.1111/1523-1747.ep12392693
  4. Lee. H. Y. (2004) A natural substances cosmetics. NEW BT, 35-41. Korea
  5. De philippis. R. M. Vincenzni, (1998) Exopolysaccharides from Cyanobacteria and their possible applications. FEMS Microbiol. Rev. 22, 151-175 https://doi.org/10.1016/S0168-6445(98)00012-6
  6. Chihara, G, Hamuro, J., Maeda, Y., Ami, Y. and Fukuoka, F. (1970) Fractionation and purification of the polysaccharides with marked antitumor activity, especially lentinan, from Lentinus edodes (Berk.) Sing. (an edible mushroom). Cancer Res. 30, 2776-2781
  7. Kosuge, T., Yokota, M., Sugiyama, K, Yamamoto, T., Ni, M. Y. and Yan, S. C. (1985) Studies on antitumor activities and antitumor principles of Chinese herbs. I. Antitumor activities of Chinese herbs. Yakugaku Zasshi. 105, 791-795
  8. Ryu, B. H., Kim, D. S., Cho, K. J. and Sin, D. B. (1989) Antitumor activity of seaweeds toward sarcoma-180. Korean J Food Sci Technol. 21, 595-600
  9. Du, Notiy, (1926) 'Surface Equilibris of Colloids'. J. J. Little and Ives Co., New York
  10. Lee, M. S., Cho, H. Y. and Lee, Y. B. (2002) Preparation and evaluation of mutivitamin emulsion. J. Kor. Pharm. Sci. 32, 13-19
  11. Lee, S. H., An, S. K. and Lee, J. O. (2000) A study on the preparation of UPE resins with different glycol molar ratios and their physical properties: 3. estimation of viscoelastic and critical surface tension of UPE liquid resins. Polymer Korea 24, 589-598
  12. Oh, J. Y., Han, C. G. and Zhoh, C. K. (1995) A study on the formation region, droplet size and stability of o/w microemulsion. J. Soc. Cosmet. Scientists Korea 21, 22-48
  13. Chung, H. S., Kim, T. W., Kwon, M. Y., Kwon, I. C. and Jeong, S. Y. (2001) Oil components modulate physical characteristics and function of the natural oil emulsions as drug or gene delivery system. J. Control. Release. 71, 339-350 https://doi.org/10.1016/S0168-3659(00)00363-1
  14. Kim, S. H., Nah, J. W. and Song, K. D. (2000) Enhancement of mechanical properties of EVA emulsion. Applied Chemistry. 4, 280-283
  15. Park, J. O. (1994) Rotational Rheometry for polymeric materials (I): Basic concepts in Rheology. Polymer (Korea), 5, 275-284
  16. Dennis, Laba. (1993) The flow of cosmetics and toiletries: Rheological properties of cosmetics and toiletries. Cosmetic Science and Technology Series. 13, 26-34
  17. Zs, Nemeth., L, Halasz., J, Palinkas., A, B?ta. and T, Horanyi, (1998) Rheological behaviour of a lamellar liquid crystalline surfactant-water system. Colloids and Surfaces. 145, 107-119 https://doi.org/10.1016/S0927-7757(98)00576-7
  18. Lee, S. J., Ro, Y. C. and Nam, K. D. (1996) The characteristics of a fine O/W emulsion by nonaqueous emulsification. J. Kor. Ind. Eng. Chem. 7, 145-152
  19. D, Balzer., S, Varwig. and M, Weihrauch. (1995) Viscoelasticity of personnal care products. Colloids and Surfaces. 99, 233-246 https://doi.org/10.1016/0927-7757(95)03144-3
  20. Kassem, M. A. and Mattha, A. G. (1971) Rheological studies on dispersions of Guaran. I. General flow characteristics. Pharm. Acta. Helv. 46, 75-82
  21. J.B: Wilkinson, R. J. Moore (Eds.). (1982) Harry's cosmeticology. Chemical Publishing Co., Inc, New York. p. 749
  22. Gallarate, M., Carlotti, M. E., Trotta, M. and Bovo, S. (1999) On the stability of ascorbic acid in emulsified system for topical and cosmetic use. Int. J. Pharm. 188, 233-241 https://doi.org/10.1016/S0378-5173(99)00228-8
  23. Carlo, A., Anna, M. M., Chiara, S. and Donatella, V. (2001) Stability studies of new cosmetic formulations with vegetable extracts as functional agents. Farmaco, 56, 427-431 https://doi.org/10.1016/S0014-827X(01)01055-2
  24. Roland, I., Piel, G, Delattre, L. and Evrard, B. (2003) Systematic characterization of oil-water emulsions for formulation design. Int. J. Pharm, 263, 85-94 https://doi.org/10.1016/S0378-5173(03)00364-8
  25. M, Bury., J, Gerhards., W, Erni. and A, Stamm. (1995) Application of a new method based on conductivity measurements to determine the creaming stability of o/w emulsions. Int. J. Pharm, 124, 183-194 https://doi.org/10.1016/0378-5173(95)00075-T
  26. Dennis, M., Eva-Maria, W., Angelika, T., Christine, T. and Heinz, H. (1999) O/W emulsions for cosmetics products stabilized by alkyl phosphates rheology and storage tests. Colloids and Surfaces. 152, 155-160 https://doi.org/10.1016/S0927-7757(98)00630-X
  27. Waggoner, W. C. ed. (1990) Clinical safety and efficacy testing of cosmetic. Cosmetic Science and Technology Series. New York, Marcel Dekker, 105
  28. Matsumura, H., Oka, K., Umekage, K., Akita, H., Kawai, J., Kitazawa, Y., Suda, S., Tsubota, K., Ninorniiya, Y. and Hirai, H. et al. (1995) Effect of occlusion on human skin. Contact Dermatitis 33, 231-235 https://doi.org/10.1111/j.1600-0536.1995.tb00472.x
  29. Aberer, W., Andersen, K. E. and White, I. R. (1993) Should patch testing be restricted to dermatologists only. Contact Dermatitis 28, 1-2 https://doi.org/10.1111/j.1600-0536.1993.tb03314.x
  30. Kim, J. I. (1997) Perspective views of evaluation methods of cosmetic safety and efficacy. J. of the Society of Cosmetic Scientists of Korea, 23, pp. 159-184, Korea