Applied Biological Chemistry

The Korean Society for Applied Biological Chemistry (한국응용생명화학회)
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Antioxidant, Anticancer and Tyrosinase Inhibition Activities of Extracts from Rhododendron mucronulatum T.

진달래꽃(Rhododendron mucronulatum Turczaninow) 추출물의 항산화, 항암 효과 및 tyrosinase 저해활성

  • An, Bong-Jeun (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Lee, Chang-Eon (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Son, Jun-Ho (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Lee, Jin-Young (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Choi, Gui-Hyang (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Park, Tae-Soon (Department of Cosmeceutical Science, Daegu Haany University)
  • 안봉전 (대구한의대학교 화장품약리학과) ;
  • 이창언 (대구한의대학교 화장품약리학과) ;
  • 손준호 (대구한의대학교 화장품약리학과) ;
  • 이진영 (대구한의대학교 화장품약리학과) ;
  • 최귀향 (대구한의대학교 화장품약리학과) ;
  • 박태순 (대구한의대학교 화장품약리학과)
  • Published : 2005.09.30
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Abstract

Several biological activities of Rhododendron mucronulatum were investigated. The electron donating abilities of ethanol extracts of Rhododendron mucronulatum were more than 90% at 100 ppm, 500 ppm and 1,000 ppm. Xanthine oxidase was inhibition about 46% by the ethanol extracts of R. mucronulatum at 500 ppm 48% of tyrosinase activity relating to skin-whitening was shown at 1,000 ppm. Uniquely, the anti-microbial effects of water extract and ethanol extract were shown only on Staphylococcus aureus. The water extract 1 mg/disc showed the higher activity than ethanol extract. The growth inhibition effect of each sample on lung cancer (A549) and melanoma (B16F10) cell lines were over 70% at 1,000 ppm, while the effects on the melanoma (G361) and liver cancer (HepG2) were about 50% at the same concentration.

Keywords

References

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