Cytotoxic Chemical Constituents from the Mushroom of Pholiota adiposa

  • Chung, Ill-Min (Department of Applied Life Science, College of Life & Environment Science, Konkuk University) ;
  • Kong, Won-Sik (Applied Microbiology Division, National Institute of Agricultural Science and Technology, RDA) ;
  • Lee, Oh-Kyu (Department of Applied Life Science, College of Life & Environment Science, Konkuk University) ;
  • Park, Jeong-Sik (Applied Microbiology Division, National Institute of Agricultural Science and Technology, RDA) ;
  • Ahmad, Ateeque (Department of Applied Life Science, College of Life & Environment Science, Konkuk University)
  • Published : 2005.04.30

Abstract

The compounds, 1-Linoleic-2-olein (1), stigmasterol (2), 1,4-glucopyranosyl-1',4'-glucopyranosyl-1",4"-glucopyranoside (3), 2',3'-diphosphoryl-1'-propanoxy-${\beta}$-D-glucopyranoside (4), 1-Linoleic-3-olein (5), l-(N,N,N-trimethyl ethyl amino phosphoryl)-2,3-dilinolein ion (6) and glyceryl phosphate (7) were isolated and identified from the Mushroom of Pholiota adiposa for the first time by column chromatography, TLC, UV, IR, $^1H$ and $^{13}C$ NMR, EI-MS, and FAB-MS. The compounds 1 and 2 were found to have weak cytotoxicity against P388 murine leukemia cells. However, the compounds 6 and 7 did not show any cytotoxicity.

Keywords

References

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