The Journal of Korean Obstetrics and Gynecology (대한한방부인과학회지)

The Society of Korean Medicine Obstetrics and Gynecology (대한한방부인과학회)
권호 표지

Effects of Mokhyangsaenghwa-tang and Mokhyangsaenghwa-tang plus Cervi Pantotrichum Cornu on Postpartum Recovery and Lactation

목향생화탕(木香生化湯)과 목향생화탕가녹이(木香生化湯加鹿茸)이 산후회복(産後回復) 및 유즙분비(乳汁分泌)에 미치는 영향(影響)

  • Kim, Dong Hwan (Dept. of Oriental Gynecology, College of Oriental Medicine, Kyung-Hee University) ;
  • Chun, Ho Nam (Mail Dairy Industry Co) ;
  • Cho, Jung-Hoon (Dept. of Oriental Gynecology, College of Oriental Medicine, Kyung-Hee University) ;
  • Jang, Jun-Bock (Dept. of Oriental Gynecology, College of Oriental Medicine, Kyung-Hee University) ;
  • Lee, Kyung-Sub (Dept. of Oriental Gynecology, College of Oriental Medicine, Kyung-Hee University)
  • 김동환 (경희대학교 한의과대학 부인과학교실) ;
  • 전호남 ((주)매일유업 중앙연구소) ;
  • 조정훈 (경희대학교 한의과대학 부인과학교실) ;
  • 장준복 (경희대학교 한의과대학 부인과학교실) ;
  • 이경섭 (경희대학교 한의과대학 부인과학교실)
  • Received : 2005.01.20
  • Accepted : 2005.02.03
  • Published : 2005.02.28
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Abstract

Objective : This study was conducted to investigate the effect of Mokhyangsaenghwa-tang (MS) and Mokhyangsaenghwa-tang plus Cervi Pantotrichum Cornu (MS-C) on postpartum recovery and lactation. Materials and Methods : We used 18-week pregnant Spraque Dawley rats and administered the decoctions of MS and MS-C to rats once a day for 4 days or 8 days. Then we observed changes in the body weight of pup rats and complete blood cell count, liver function test, renal function test, mammary gland tissue, level of serum prolactin, ${\beta}-casein$ and WAP of postpartum rats. Result : A significant increase in body weight was observed in MS-C treated pup rats compared with in MS treated group. The levels of WBC and platelet from MS group and MS-C group were decreased compared with the control group. The levels of RBC, hemoglobin and hematocrit from MS group and MS-C group showed statistically significant increases compared with the control group. The levels of protein, albumin from MS group and MS-C group were increased compared with the control group. The levels of BUN, creatinine from MS group and MS-C group did not show statistically significant changes compared with the control group. The mammary gland tissues from MS group and MS-C group showed increased angiogenesis. The levels of serum prolactin from MS group and MS-C group were increased compared with the control group. The expression of ${\beta}-casein$ and WAP genes from postpartum rats treated with MS and MS-C was increased. Conclusion : This study shows that MS and MS-C improved postpartum recovery and lactation in rats.

Keywords

References

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