Korean Circulation Journal

The Korean Society of Cardiology (대한심장학회)
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Multicenter Analysis of Clinical Characteristics and Prognostic Factors of Patients with Congestive Heart Failure in Korea

한국인 심부전 환자의 임상특성 및 예후인자에 관한 다기관 연구

Han, Seong-Woo;Ryu, Kyu-Hyung;Chae, Shung-Chull;Yang, Dong-Heon;Shin, Mi-Seung;Lee, Sang-Hoon;Jeon, Eun-Seok;Oh, Byung-Hee;Choi, Dong-Ju;Kim, Jae-Joong;Shin, Dong-Gu;Ryu, Byung-Soo;Ahn, Yung-Geun
한성우;유규형;채성철;양동헌;신미승;이상훈;전은석;오병희;최동주;김재중;신동구;유병수;안영근

  • Published : 2005.05.30
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Abstract

Background and Objectives：Congestive heart failure is one of the most frequent problems in cardiovascular patients. The objectives of this study were to evaluate the demographic and clinical characteristics and prognostic factors of patients hospitalized with congestive heart failure in Korea. Subjects and Methods：Nine university hospitals were involved, and gathered prospective clinical data on patients with heart failure. One thousand eight hundred and sixty four patients, admitted between Jan.1 1998 and Aug. 31 2003, were enrolled, and data from 1,759 patients were analyzed. Results：The cumulative survival rates at 6 month, and 1 and 2 years were 90.8, 80.1 and 76.4%, respectively. Ischemic heart disease was the most frequent underlying disease (32.3%). Diabetes mellitus (OR: 1.682, 95%CI: 1.234-2.389, p=0.005), a previous history of myocardial infarction (OR: 2.521, 95%CI: 1.742- 4.258, p<0.0001) and cerebrovascular accidents (OR: 2.020, 95%CI: 1.166-3.101, p=0.001) were the worst prognostic factors. Conclusion：Ischemic heart disease was the major cause of heart failure. The two year survival rate of patients with congestive heart failure was 76.4%. The factors relating to a poor prognosis were diabetes, a previous history of myocardial infarction and cerebrovascular accident.

배경 및 목적：울혈성 심부전의 원인 질환 및 자연 경과, 예후인자에 대한 국내의 자료는 드문 실정이다. 본 연구는 국내 울혈성심부전 환자의 기본적인 역학적 특성과 임상양상에 대한 자료를 파악하기 위하여 9개 의과대학이 참여한 전향적 연구이다.방 법：1998년 1월 1일부터 2003년 8월 31일까지 국내 9개 대학병원에 울혈성 심부전으로 입원한 1,864명의 환자를 대상으로 하였다. 생존에 영향을 미칠 수 있는 다른 질환이 동반된환자를 제외한 1,759명의 자료를 분석하였고 생존률 및 예후인자를 분석하였다.결 과：국내 울혈성 심부전 환자의 원인 질환은 허혈성 심장질환이 32.3%로 가장 많았고 확장성 심근증을 포함한 심근질환이22.7%, 고혈압성 심장질환 16.5%, 심장 판막증이 13.5%였다.전체환자의 6개월, 1년, 2년 누적생존률은 각각 90.8%, 80.1%,76.4%였다. 심근경색의 과거력(OR: 2.521, 95%CI: 1.742~4.258, p<0.0001), 당뇨병(OR: 1.682, 95%CI: 1.234~2.389,p=0.005), 뇌혈관사고(OR: 2.020, 95%CI: 1.166~3.101, p=0.001) 등이 불량한 예후인자였다.결 론：허혈성 심장질환은 국내 울혈성 심부전 환자의 가장 흔한원인 질환이었다. 2년 생존률은 76.4%였고 당뇨병과 심근경색병력, 뇌졸중 등은 국내 울혈성 심부전 환자의 불량한 예후환자였다.

Keywords

References

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