Exercise Science (운동과학)

korean Society of Exercise Physiology (한국운동생리학회)
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Effects of one year exercise training program on the impaired fasting glucose, cardiovascular risk factors andaerobic exercise capacity in middle aged men

1년간의 운동 트레이닝이 중년 남성의 공복혈당장애 개선과 심혈관계 질환 위험 지표 및 유산소성 운동 능력에 미치는 영향

Kim, H.J.;Kim, C.K.
김효정;김창근

  • Published : 20050500
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Abstract

This study was performed to investigate the effect of one year exercise training on cardiovascular risk factors, blood glucose and aerobic exercise capacity in middle aged men with impaired fasting glucose level. The subjects (90 males, 41 - 57 years) were divided to Control (n=32), Normal (training, n=40), and IFG (impaired fasting glucose concentration, n=18) group according to the presence of training or IFG. Waist circumference, blood pressure, fasting glucose, triglyceride, HDL-cholesterol, $VO_2max$ (maximal oxygen uptake), AT (anaerobic threshold) and HRmax were measured at baseline and after one year of exercise training. Aerobic exercise training consisted of treadmill running at 60-70% of $VO_2max$ (30 minutesㆍday-1, 3 days, $week^{-1}$) and resistance training performed three sets of lifts using 60-70% of 1RM to complete each of 8 rpt/set (3 daysㆍ$week^{-1}$) during one year. Waist circumference, triglyceride, HDL-cholesterol, $VO_2max$, AT in Training group (Normal and IGT group) were changed significantly by training (p<.05) and there was no differences of training effect between those two groups. But, all cardiovascular risk factors and aerobic exercise capacity in Control group were unchanged after one year. On the other hands, there were significant negative correlation between aerobic capacity and cardiovascular risk factors (waist, blood pressure, and triglyceride, p<.05). These results support that long term exercise training program combined aerobic and resistance training can be effective regimen to prevent cardiovascular disease in middle aged men with impaired fasting glucose.

이 연구는 심혈관 질환 발병 위험이 높은 중년 남성을 대상으로 1년 동안 유산소운동과 저항성 운동을 복합 처방한 운동프로그램의 장기 시행에 의한 심혈관 질환 예방효과를 검증하고공복혈당 장애 상태가 트레이닝 효과에 영향을 미치는지 검증하고자 수행되었다. 대사 장애가 없는 정상 트레이닝군(n=40), 공복시 혈당장애를 나타내는 IFG 트레이닝군(n=18), 대조군(n=32) 으로 구성된 중년 남성 90명(41-57세)을 대상으로 1년간 유산소성 운동(최대산소섭취량의 60-70%의 강도로 1일 30분씩 트레드밀 달리기)과 저항성 운동(1RM의 60-70%로 8회 반복하여 매회 3세트 시행)을 복합한 운동 트레이닝을 주당 3회 실시하였으며 심혈관 질환 위험지표인 허리 둘레, 혈압, 공복시 혈당, 혈중 중성지방, 혈중 고밀도 지질 농도, 최대산소섭취량, 무산소성 한계점(AT) 등을 측정하였다. 1. 심혈관 질환 위험지표 변화를 분석한 결과 트레이닝에 의해 허리둘레(waist circumference)와 혈중 중성지방이 감소되고 HDL-C 농도가 증가하는 변화를 보였으며 IFG group인 경우에도 정상인과 같은 수준으로 TG와 HDL-C 농도가 개선되는 결과를 나타냈다(p<.05). 2. 운동 트레이닝 수행 후 정상 트레이닝군과 IFG 트레이닝군의 최대산소섭취량($VO_2max$)과 무산소성 역치가 증가하였다(p<.05). 3. 유산소성 운동능력과 심혈관 질환 위험지표의 상관관계를 분석한 결과에서 최대산소섭취량($VO_2max$)은 연령, 체중, 허리둘레 및 TG와 상관을 보였으며 무산소성 역치(AT)는 체지방과 TG, HRmax는 연령, DBP(이완기 혈압)와 상관을 나타냈다(p<.05).이상의 결과를 통해 유산소와 저항성 운동을 포함하는 운동 프로그램을 규칙적으로 장기간 수행할 경우 심혈관 질환을 일으키는 위험지표들이 개선되는 효과를 확인하였으며 각 변인들과의 상관관계 분석을 통해 심혈관계 질환 예방을 위해서는 유산소성 운동 능력을 향상시키고 혈중 지질을 개선하며 복부지방을 감소시키는 트레이닝이 필요함을 알 수 있었다. 또한 이 연구는 장기간의 운동 트레이닝에 의한 심혈관계 질환 위험지표 개선 효과는 심혈관 질환 발병 위험이 높은 공복혈당 장애 환자인 경우에도 정상인과 유사한 수준의 긍정적인 개선 효과를 나타낼 수 있음을 시사한다.

Keywords

References

  1. 김영길, 차광석 (1996). 중년 남성의 유산소성 운동능력과 심혈관질환 인자와의 관계. 서울산업대학원 논문집, 44, 585-595
  2. 유인상, 강동호, 박노원, 오정열, 이원근(1997). 체중증가가 심혈관계 위험요인에 미치는 영향. 가정의학회지, 18(7), 722-730
  3. 2003년 통계청 사망원인연보(2004). 대전: 통계청, 대한영상미디어
  4. 차광석 (1999). 전문가를 위한 최신 운동처방론. 서울: 체육과학연구원
  5. Banz, W.J., Maher, M.A., Thompson, W.G., Bassett, D.R., Moore, W, Ashraf, Keefer, D.J., & Zemel, M.B(2003). Effects of resistance versus aerobic training on coronary artery disease risk factors. Exp BioI Med, 228, 434-440
  6. Beckham, S.G. & Earnest, C.P.(2000). Metabolic cost of free weight circuit weight training. J Sports Med Phys Fitness, 40(2), 118-125
  7. Booth, F.W., Gordon, S.E., Carson, C.J & Hamilton, M.T(2000). Waging war on modem chronic diseases: primary prevention through exercise biology. J Appl Physiol, 88, 774-787
  8. Bjorntorp, P.(1996). The regulation of adipose tissue distribution in humans. Int J Obs, 20, 291 -302
  9. Carlson, L.A., Hallberg, D., Micheli, H(1969). Quantitative studies on the lipolytic response of human subcutaneous and omental adipose tissue to noradrenalin and theophyline. Acta Med Scand 185, 465-469 https://doi.org/10.1111/j.0954-6820.1969.tb07368.x
  10. Casaburi, R.(2000). Skeletal muscle function in COPD. Chest, 117, 276S-271S
  11. Frontera, W.R., Meredith, C.N., O'Reilly, K.P., Evans, W.J.(1990). Strength training and determinants of VO2max in older men. J Appl Pltysiol, 68, 329-333
  12. Eriksson J, Tuominen J, Valle T, Sundberg S, Sovijarvi A, Lindholm H, Tuomilehto J, & Koivisto V.(1998). Aerobic endurance exercise or circuit-type resistance training for individuals with impaired glucose tolerance? Horm Metab Res. J 30(1): 37-41 https://doi.org/10.1055/s-2007-978828
  13. Honkola A, Forsen T, & Eriksson J. (1997). Resistance training improves the metabolic profile in individuals with type 2 diabetes. Acta Diabetol. 34(4): 245-248 https://doi.org/10.1007/s005920050082
  14. Giada, F., Vigna, G.B., Vitale, E., Baldo-Enzi, G., Bertaglia, M., Crecca, R, & Fellin, R(1995). Effect of age on the response of blood lipids, body composition, and aerobic power to physical conditioning and deconditioning. Metabolism, 44(2), 161-165 https://doi.org/10.1016/0026-0495(95)90259-7
  15. Gosselink, R, Troosters, T., & Decramer, M.(1996). Peripheral muscle weekness contributes to exercise limitation in COPD. Am J Respir Crit Care Med, 153, 976-980 https://doi.org/10.1164/ajrccm.153.3.8630582
  16. Hamilton, A.L., Killian, K.J., Summers, E., Jones, N.L.(1995). Muscle strength, symptom intensity, and exercise capacity in patients with cardiorespiratory disorders. Am J Respir Crit Care Med, 152, 2021-2031 https://doi.org/10.1164/ajrccm.152.6.8520771
  17. Kaikkonen, H., Yrjama, M., Siljander, E., & Byman, P., & Laukkanen, R(2000). The effect of heart rate controlled low resistance circuit weight training and endurance training on maximal aerobic power in sedentary adults. Scand J M ed Sci Sports, 10(4), 211-215 https://doi.org/10.1034/j.1600-0838.2000.010004211.x
  18. LeMura, L.M, von Duvillard, S.P., Andreacci, J., KIebez, J,M., Chelland, S.A, & Russo, J,(2000). Lipid and lipoprotein profiles, cardiovascular fitness, body composition, and diet during and after resistance, aerobic and combination training in young women. Eur J Appl Physiol, 82(5-6), 451-458 https://doi.org/10.1007/s004210000234
  19. Mador, M.J. & Bozkanat, E.(2001). Skeletal muscle dysfunction in chronic obstructive pulmonary disease. Respir Res, 2, 216-224 https://doi.org/10.1186/rr60
  20. Maltais F., Simard, A.A, Simard, C., Jobin, J. Desgenes, P., Leblanc, P., & Janvier, R(1996). Oxidative capacity of the skeletal muscle and lactic acid kinetics during exercise in normal subjects and in patients with COPD. Am J Respir Crit Care Med, 153, 288-293 https://doi.org/10.1164/ajrccm.153.1.8542131
  21. Motoyama, M, Sunami, Y., Kinoshita, F., Irie, T., Sasaki, J., Arakawa, K, Kiyonaga, A, Tanaka, H., Shindo, M(1995). The effects of long-term low intensity aerobic training and detraining on serum lipid and lipoproteins in elderly men and women. Eur J Appl Physiol Occup Pltysiol, 70(2), 126-31 https://doi.org/10.1007/BF00361539
  22. Munter, P., He, J., Chen, j, Fonseca, V., Whelton, P.K.(2004). Prevalence of non-traditional cardiovascular diseaserisk factors among persons with impaired fasting glucose, impaired glucose tolerance, diabetes, and metabolic Syndrome: analysis of the Third National Health and Nutrition Examination Survey (NHANES lII). Ann Epidemiol. 14(9), 686-695 https://doi.org/10.1016/j.annepidem.2004.01.002
  23. Ortega, F., Toral, J. Cejudo, P., Villagomez, R, Sanchez, H., Castillo, Jose, & Montemayor, T.(2002). Comparison of effects of strength and endurance training in patients with chronic obstructive pulmonary disease. Am J Respir Crit Med. 166; 669-674 https://doi.org/10.1164/rccm.2107081
  24. Pan, D.A., Lillioja, S., Kriketos, A.D., Milner, M.R, Baur, L.A, Bogardus, C., Jenkins, A.B., & Storlien, L.H.(1997). Skeletal muscle triglyceride levels are inversely related to insulin action. Diahetes, 46, 983-988
  25. Peltonen, J.E .. , Taimela, S., Erkintalo, M., Salminen, J.J., Oksanen, A, & Kujala, U.M.(1997). Back extensor and psoas muscle cross-sectional area, prior physical training, and trunk muscle strength a longitudinal study in adolescent girls. Eur J Appl Physiol, 77, 66-71 https://doi.org/10.1007/s004210050301
  26. Petibois, C, Cassaigne, A, Gin, H., & Deleris, G.(2004). Lipid profile disorders induced by long-term cessation of physical activity in previously highly endurancetrained subjects. J Clin Endocrinol Metab, 89(7), 3377-3384 https://doi.org/10.1210/jc.2003-031311
  27. Robert J. Ferry, Jr. Ruben W. Cerri Pinchas Cohen,(1999). Insulin-Like Growth Factor Binding Proteins: New Proteins, New Functions. Horm Res. 51:53-67 https://doi.org/10.1159/000023315
  28. Russell, J.C., Shillabeer, G., & Bar-Tana J.(1998), Development of insulin resistance in the JCR: LA -cp rat: Role of triacylglycerols and effects of MEDICA 16. Diabetes, 47, 770-778 https://doi.org/10.2337/diabetes.47.5.770
  29. Sheperd R.J. & Balady G.J,(1999) Exercise as cardiovascular therapy. Circulation 99, 963-972 https://doi.org/10.1161/01.CIR.99.7.963
  30. Spratt K.A.(2004). Reducing the risk of coronary heart disease Via lipid reduction. J Am Osteopath Assoc. 104(9 suppl 7), S9-S13
  31. Storgaard, H., Song, X.M., Jensen, C.B, Madsbad, S., Bjomholm, M., Vaag, A., Zierath, JR. (2001) Insulin signal transduction in skeletal muscle from glucose- intolerant relatives with type 2 diabetes. 2001, 50(12), 2770-2778
  32. Svedberg, J., Bjortorp, P., Smith, U, & Lonroth, P.(1990). Free-fatty acid inhibition of insulin binding, degradation and action in isolated rat hepatocytes. Diabetes. 39, 570-574 https://doi.org/10.2337/diabetes.39.5.570
  33. Tanasescu, M., Leitzmann, M.F., Rimm., E.B., Willett, W.C., Stampfer, M.J., & Hu, F.B.(2002). Exercise type and intensity in relation to coronary heart disease in men. JAMA. 288(16), 1994-2000 https://doi.org/10.1001/jama.288.16.1994
  34. Tokmakidis, S.P. & Volaklis, K.A.(2003). Training and detraining effects of a combined-strength and aerobic exercise program on blood lipids in patients with coronary artery disease. J Cardiopulm Rehabil, 23(3), 193-200 https://doi.org/10.1097/00008483-200305000-00006
  35. Warburton, D.E., Haykowsky, M.J., Quinney, H.A, Blackmore, D., Teo, K.K., Taylor, D.A, McGavock, J & Humen, D.P. (2004). Blood volume expansion and cardiorespiratory function: effects of training modality. Med Sci Sports Exerc, 36(6), 991-1000 https://doi.org/10.1249/01.MSS.0000128163.88298.CB
  36. Watkins, L.L., Sherwood, A., Feinglos, M., Hinderliter, A., Babyak, M., Gullette, E., Waugh, R & Blumental, J.A.(2003). Effects of exercise and weight loss on cardiac risk factors associated with syndrome. Arch Intern Med. 163(16), 1889-1895 https://doi.org/10.1001/archinte.163.16.1889
  37. Weir, L.L., Weir, J.P., Housh, T.J, & Johnson, G.O.(1997). Effect of an aerobic training program on physical working capacity at heart rate threshold. Eur J Appl Physiol Occup Physiol, 75(4), 351-356 https://doi.org/10.1007/s004210050171
  38. Westcott, W.L., Winett, R.A., Anderson, E.S., Wojcik, J.R, Loud, R.L., Cleggett, & E., Glover, S.E.(2001). Effects of regular and slow speed resistance training on muscle strength. J Sports Med Phys Fitness, 41(2), 154-158
  39. Williams, T. F. (1996). Assessment of mobility and hand function in the elderly. Isr J Me. Sci, 22, 220-225