References
- Wilson PD : Polycystic kidney disease. N Engl J Med 350:151-164, 2004 https://doi.org/10.1056/NEJMra022161
- Murcia NS. Sweeney WE, Avner ED: New insights into the molecular pathophysiology of polycystic kidney disease. Kidney Int 55:1187-1197, 1999 https://doi.org/10.1046/j.1523-1755.1999.00370.x
- Veis DJ, Sorenson CM, Shutter JR, Korsmeyer SJ : Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell 75:229-240, 1993 https://doi.org/10.1016/0092-8674(93)80065-M
- Woo D: Apoptosis and loss of renal tissue in polycystic kidney diseases. N Engl J Med 333: 18-25, 1995 https://doi.org/10.1056/NEJM199507063330104
- Hengartner MO: The biochemistry of apotosis. Nature 407:770-776, 2000 https://doi.org/10.1038/35037710
-
Schuster N, Krieglstein K: Mechanism of
$TGF-{\beta}-mediated$ apoptosis. Cell Tissue Res 307:1-14, 2002 https://doi.org/10.1007/s00441-001-0479-6 -
Bottinger EP, Bitzer M:
$TGF-{\beta}$ signaling in renal disease. J Am Soc Nephrol 13:2600-2610, 2002 https://doi.org/10.1097/01.ASN.0000033611.79556.AE -
Derynck Rik, Zhang YE: Smad-dependent and Smad-independent pathways in
$TGF-{\beta}$ family signalling. Nature 425:577-584, 2003 https://doi.org/10.1038/nature02006 - Schiffer M, Bitzer M, Roberts IS, Kopp JB, ten Dijke P, Mundel P, Bottinger EP: Apoptosis in podocytes induced by TGF-beta and Smad7. J Clin Invest 108:807-816, 2001
- Savill J : Apoptosis and the kidney. J Am Soc Nephrol 5:12-21, 1994
- Ortiz-Arduan A, Danof TM, Kalluri R, Gonzalez-Cuadrado S, Karp SL, Elkon K, Egido J, Neilson EG: Regulation of Fas and Fas ligand expression in cultured murine renal cells and in the kidney during endotoxemia. Am J Physiol 271:F1193-F1201, 1996
- Liberthal W, Levin JS: Mechanism of apoptosis and its potential role in renal tubular epithelial cell injury. Am J Physiol 271:F477-488, 1996
- Sprick MR, Walczak H: The interplay between the Bcl-2 family and death receptor-mediated apoptosis. Biochim Biophys Acta 1644:125-132, 2004 https://doi.org/10.1016/j.bbamcr.2003.11.002
- Frisch SM, Francis H: Disruption of epitherial cell-matrix interactions induces apoptosis, J Biol 124:619-626, 1994
- Aoshiba K, Rennard SI, Spurzem JR: Cell-matrix and cell-cell interactions modulate apoptosis of bronchoal epitherial cells. Am J Physiol 2772: L28-L37, 1997
- Lallemand F, Mazars A, Prunier C, Bertrand F, Kornprost M, Gallea S, Roman-Roman S, Cherqui G, Atfi A: Smad7 inhibits the survival nuclear factor kappals and potentiates apoptosis in epithelial cells. Oncogene 20:879-884, 2001 https://doi.org/10.1038/sj.onc.1204167
- Motyl T, Grzelkowska K, Zimowska W, Skierski J, Wareski P, Ploszaj T, Trzeciak L: Expression of bcl-2 and bax in TGF-beta 1-induced apoptosis of L1210 leukemic cells. Eur J Cell Biol 75:367-374, 1998 https://doi.org/10.1016/S0171-9335(98)80070-8
- Francis JM, Heyworth CM, Spooncer E, Pierce A, Dexter TM, Whetton AD : Transforming growth factor-beta 1 induces apoptosis independently of p53 and selectively reduces expression of Bcl-2 in multipotent hematopoietic cells. J Biol Chem 275:39137-39145, 2000 https://doi.org/10.1074/jbc.M007212200
- Chipuk JE, Bhat M, Hsing AY, Ma J, Danielpour D : Bcl-xL blocks transforming growth factorbeta 1-induced apoptosis by inhibiting cytochrome c release and not by directly antagonizing Apaf-1-dependent caspase activation in prostate epithelial cells. J Biol Chem 276:26614- 26621, 2001 https://doi.org/10.1074/jbc.M100913200
- Torres VE: Apopotosis in cystogenesis : Hands on or hands off? Kidney Int 55:334-335, 1999 https://doi.org/10.1046/j.1523-1755.1999.00262.x
- Coles HSR, Burne JF, Raff MC: Large-scale normal cell death in the developing rat kidney and its reduction by epidermal growth factor. Development 118:777-784, 1993
- Oriz A: Apoptotic regulatory proteins in renal injury. Kidney Int 58:467-485, 2000 https://doi.org/10.1046/j.1523-1755.2000.00188.x
- Nadasdy T, Laszik Z, Lajoie G, Blick KE, Wheeler DE, Silva FG: Proliferative activity of cyst epithelium in human renal cystic diseases. J Am Soc Nephrol 5:1462-1468, 1995
- Zhou XJ, Kukes G: Pathogenesis of autosomal dominant polycystic kidney disease: Role of Apoptosis, Diagn Mol Pathology 7:65-68, 1998 https://doi.org/10.1097/00019606-199804000-00001
- Lanoix J, D' Agati V, Szabolcs M, Trudel M: Dysregulation of cellular proliferation and apoptosis mediates human autosomal dominant poly cystic kidney disease (ADPKD). Oncogene 13: 1153-1160, 1996
- Nagata M, Nakauchi H, Nakayama KI, Nakayama K, Loh D, Watanabe T: Apoptosis during an early stage of nephrogenesis induces renal hypoplasia in bcl-2-deficient mice. Am J Pathol 148:1601-1611, 1996
- Sorenson CM, Padanilam BJ, Hammerman MR: Abnormal postpartum renal development and cystogenesis in the bcl- 2 (- / -) mouse. Am J Physiol 271:F184-F193, 1996
-
Moser M, Pscherer A, Roth C, Becker J, Mucher G, Zerres K, Dixkens C, Weis J, Guay-Woodford L, Buettner R, Fassler R : Enhanced apoptotic cell death of renal epithelial cells in mice lacking transcription factor
$AP-2{\beta}$ . Genes Dev 11 :1938-1948, 1997 https://doi.org/10.1101/gad.11.15.1938 - Trudel M, D' Agati V, Costantini F: C-myc as an inducer of polycystic kidney disease in trans genic mice. Kidney Int 39:665-671, 1991 https://doi.org/10.1038/ki.1991.80
- Trudel M, Barisoni L, Lanoix J, D' Agati V: Polycystic kidney disease in SBM transgenic mice: role of c-myc in disease induction and progression. Am J Pathol 152:219-229, 1998
- Lin HH, Yang TP, Jiang ST, Yang HY, Tang MJ : BCI-2 overexpression prevents apoptosis induced-Madin-Darby canine kideny simple epithelial cyst formation. Kidney Int 55:168-178, 1999 https://doi.org/10.1046/j.1523-1755.1999.00249.x
- Ecder T, Melnikov VY, Stanley M, Korular D, Lucia MS, Schrier RW, Edelstein CL: Caspases, Bcl-2 proteins and apoptosis in autosornal-dominant polycystic kidney disease. Kidney Int 61: 1220-1230, 2002 https://doi.org/10.1046/j.1523-1755.2002.00250.x
- Trudel M, Lanoix J, Barisoni L, Blouin MJ, Desforges M, L'Italien C, D' Agati VD: C-MYC-induced apoptosis in polycystic kidney disease is Bd-2 and p53 independent. J Exp Med 186: 1873-1884, 1997 https://doi.org/10.1084/jem.186.11.1873