Korean journal of aerospace and environmental medicine (항공우주의학회지)

Aerospace Medical Association of Korea (한국항공우주의학협회)
권호 표지

Weightlessness-simulated Experimental Apparatus: Hindlimb Unloading Model in Rat-Technical Aspects

Hwang, Sang-Ho;Jung, Chan-Kwon

  • Published : 2005.08.30
⟨ Previous Next ⟩

Abstract

Keywords

References

  1. Park E and Schultz E. A simple hindlimb suspension apparatus. Aviat Space Environ Med 1993;64:401-404
  2. Morey-Holton ER and Globus RK. Hindlimb unloading rodent model: technical aspects. J Appl Physiol 2002;92:1367-1377 https://doi.org/10.1063/1.1492860
  3. Morey ER. Spaceflight and bone turnover: correlation with a new rat model of weightlessness. Bioscience 1979;29:168-172 https://doi.org/10.2307/1307797
  4. Wronski TJ and Morey-Holton ER. Skeletal response to simulated weightlessness: a comparison of suspension techniques. Aviat Space Environ Med 1987;58:63-68
  5. Ilin EA and Novikov VE. Stand for modelling the physiological effects of weightlessness in laboratory experiments with rats. Kosm Biol Aviakosm Med 1980; 14:79-80
  6. Halloran BP, Bikle DD, Cone CM, Morey-Holton E. Glucocorticoids and inhibition of bone formation induced by skeletal unloading. Am J Physiol Endocrinol Metab 1988;255:E875-E879 https://doi.org/10.1152/ajpendo.1988.255.6.E875
  7. Steffen JM and Musacchia XJ. Disuse atrophy, plasma corticosterone, and muscle glucocorticoid receptor levels. Aviat Space Environ Med 1987;58:996-1000
  8. Hargens AR, Steskal J, Johansson C, Tipton CM. Tissue fluid shift, forelimb loading, and tail tension in tail suspended rats. Physiologist 1984;27:S37-S38
  9. Cosmos 2044 mission. J Appl Physiol 1993;73:1S-200S
  10. Chapes SK, Mastro AM, Sonnenfeld G, Berry WD. Antiortbostatic suspension as a model for the effects of space-flight on the immune system. J Leukoc Biol 1993;54:227-235 https://doi.org/10.1002/jlb.54.3.227
  11. Morey-Holton ER and Globus RK. Hindlimb unloading of growing rats: a model for predicting skeletal changes during space flight. Bone 1998;22:83S-88S. https://doi.org/10.1016/S8756-3282(98)00019-2
  12. Tischler ME, Henriksen EJ, Munoz KA, Stump CS, Woodman CR, Kirby CR. Spaceflight on STS-48 and eartbbased unweighting produce similar effects on skeletal muscle of young rats. J Appl Physiol 1993;74:2161-2165 https://doi.org/10.1152/jappl.1993.74.5.2161
  13. Vico L, Novikov VE, Very JM, Alexandre C. Bone bistomorphometric comparison of rat tibial metaphysis after 7-day tail suspension vs. 7-day spaceflight. Aviat Space Environ Med 1991;62:26-31
  14. Hardley JA, Hall JC, O'Brien A, Ball R. Effects of a simulated microgravity model on cell structure and function in rat testis and epididymis. J Appl Physiol 1993;2:748-759