Journal of Veterinary Science

The Korean Society of Veterinary Science (대한수의학회)
권호 표지

The anti-thrombotic activity of surfactins

Lim, Jong-Hwan;Park, Byung-Kwon;Kim, Myoung-Seok;Hwang, Mi-Hyun;Rhee, Man-Hee;Park, Seung-Chun;Yun, Hyo-In

  • Published : 20051200
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Abstract

Platelet aggregation was inhibited and the density of platelet-rich plasma (PRP) clots was decreased by the preincubation of PRP with surfactins, an acidic lipopeptide of Bacillus subtilis complex BC1212 isolated from soybean paste, in dose-dependent manner. Our findings suggest that surfactins are able to prevent a platelet aggregation leading to an inhibition of additional fibrin clot formation, and to enhance fibrinolysis with facilitated diffusion of fibrinolytic agents.

Keywords

References

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