Effect of Soy Isoflavone Supplementation and Exercise on Serum Lipids in Postmenopausal Women

이소플라본 보충과 운동이 폐경 후 여성의 혈중 지질 수준에 미치는 영향

  • Choi In-Sun (Department of Food & Nutrition, Sookmyung Women's University) ;
  • Bae Yun-Jung (Department of Food & Nutrition, Sookmyung Women's University) ;
  • Jang Sul (Department of Food & Nutrition, Sookmyung Women's University) ;
  • Lee Da-Hong (Department of Food & Nutrition, Wonkwang University) ;
  • Yun Mi-Eun (Department of Food & Nutrition, Sookmyung Women's University) ;
  • Lee Haeng-Shin (Department of Food Industry, Korea Health Industry Development Institute) ;
  • Kim Mi-Hyun (Department of Food & Nutrition, Samcheok National University) ;
  • Lee Sang-Ho (Iksan Hospital) ;
  • Sung Chung-Ja (Department of Food & Nutrition, Sookmyung Women's University)
  • 최인선 (숙명여자대학교 식품영양학과) ;
  • 배윤정 (숙명여자대학교 식품영양학과) ;
  • 장설 (숙명여자대학교 식품영양학과) ;
  • 이다홍 (원광대학교 식품영양학과) ;
  • 윤미은 (숙명여자대학교 식품영양학과) ;
  • 이행신 (한국보건산업진흥원 보건의료사업단) ;
  • 김미현 (삼척대학교 식품영양학과) ;
  • 이상호 (익산병원 방사선과) ;
  • 승정자 (숙명여자대학교 식품영양학과)
  • Published : 2005.07.01

Abstract

To elucidate the effect of soy isoflavone supplementation and exercise on serum lipids in normolipidemic and mildly hyperlipidemic postmenopausal period, 54 women residing in Seoul area were recruited. The subjects were divided into 4 groups: control group (n=13), isoflavone group (n=14), exercise group (n=14), isoflavone + exercise group (n=13). The control group was given placebo capsules, isoflavone group was given soy isoflavone supplements (90 mg/day), exercise group was given placebo capsules and exercised 3 times/week, over 30 min/time, and isoflavone + exercise group took soy isoflavone supplement and exercised. The duration of study were 8 weeks. The average age of the subjects was 57.0 years, 56.0 years, 54.4 years, and 55.2 years, respectively. There were no significant differences among the four groups in terms of height, weight, and body mass index. There were no significant differences among the four groups in terms of serum, total cholesterol, HDL-cholesterol. But the subjects indicated a significant difference in serum LDL-cholesterol (110.5 mg/day in before versus 74.6 mg/day in after) in the isoflavone + exercise group at the levels of p<0.05. In conclusion, the isoflavone supplementation and exercise may be helpful to decrease serum lipids of normolipidemic and mildly hyperlipidemic postmenopausal women.

Keywords

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