Korean Journal of Medicinal Crop Science (한국약용작물학회지)

The Korean Society of Medicinal Crop Science (한국약용작물학회)
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Antioxidant Activity and Whitening Effect of Extraction Conditions in Curcuma longa L.

추출조건에 따른 울금의 항산화 및 미백 효과

  • An, Bong-Jeun (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Lee, Jin-Young (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Park, Tae-Soon (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Pyeon, Jeong-Ran (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Bae, Ho-Jung (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Song, Mi-Ae (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Baek, Eun-Ji (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Park, Jung-Mi (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Son, Jun-Ho (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Lee, Chang-Eon (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Choi, Kyung-Im (Department of Beauty Coordination, Daegu Health College)
  • 안봉전 (대구한의대학교 화장품약리학과) ;
  • 이진영 (대구한의대학교 화장품약리학과) ;
  • 박태순 (대구한의대학교 화장품약리학과) ;
  • 편정란 (대구한의대학교 화장품약리학과) ;
  • 배호정 (대구한의대학교 화장품약리학과) ;
  • 송미애 (대구한의대학교 화장품약리학과) ;
  • 백은지 (대구한의대학교 화장품약리학과) ;
  • 박정미 (대구한의대학교 화장품약리학과) ;
  • 손준호 (대구한의대학교 화장품약리학과) ;
  • 이창언 (대구한의대학교 화장품약리학과) ;
  • 최경임 (대구보건대학 뷰티코디네이션과)
  • Published : 2006.06.30
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Abstract

Curcuma longa L. of Zingiberaceae family, has been reported to have radical scavenging activity and antiinflammatory effect. On these facts, biological activity and whitening effect were examined to evaluate a bioactivity of the extracts of Curcumma longa L. by extraction conditions as a possible pharmaceutical material. When compared extraction methods, supercritical extraction was the best showing various biological activities and whitening effect. The highest electron donating ability $(89%\;at\;1,000{\mu}g/ml)$ were detected and SOD-like activity was inhibited up to $95%\;at\;500{\mu}g/ml$ in supercritical extraction. To evaluate the whitening effect, tyrosinase inhibitory activity was conducted 89% of tyrosinase inhibitory effect examined at $1,000\;{\mu}g/ml$. From these results, we suggest that the supercritical extracts from Curcuma longa L. is useful for cosmetic ingredients.

화장품에 응용 가능한 소재를 발굴하기 위한 목적으로 추출조건에 따른 울금 (Curcuma longa L.)의 항산화 효과 및 미백 효과를 수행한 결과는 다음과 같다. 1. DPPH 라디칼에 대한 소거능은 시료 농도 $1,000\;{\mu}g/ml$에서 초임계 추출 시료는 89.0%의 저해율을 나타내어, 3가지 추출법 중 초임계 추출물이 가장 높은 전자공여능을 나타내었다. 2. 울금 추출물의 SOD 유사활성을 측정한 결과 3가지 추출방법 중 초임계 추출물의 경우 시료 농도 $500\;{\mu}g/ml$에서 95.0% 가장 높은 SOD 유사활성을 나타내었다. 3. Xanthine oxidase 저해활성을 측정한 결과, 시료 농도 $1,000\;{\mu}g/ml$의 초임계 추출물에서 40%의 저해능을 나타내어 물, 에탄올, 1,3-butylene glycol 추출물에 비해 높은 효과를 나타내었다. 4. 울금 추출물의 tyrosinase 저해 활성을 측정한 결과 에탄올 및 초임계 추출물의 경우 $1,000\;{\mu}g/ml$의 농도에서 각각 82.0, 89.0%로 높은 tyrosinase 저해 활성을 나타내었다. 이상의 실험 결과를 종합해 볼 때, 울금을 이용한 4가지 추출법 중 초임계추출법이 가장 높은 항산화 효과 및 미백효과를 나타내어 화장품의 소재로서 응용이 가능할 것으로 사료된다.

Keywords

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