Applied Biological Chemistry

The Korean Society for Applied Biological Chemistry (한국응용생명화학회)
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Antioxidant Effects and Tyrosinase Inhibition Activity of Extract of Prunus sargentii Rehder

화피(樺皮)의 항산화 효과 및 tyrosinase 저해활성

  • An, Bong-Jeun (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Cho, Young-Je (Department of Food Engineering, Sangju National University) ;
  • Son, Jun-Ho (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Park, Jung-Mi (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Lee, Jin-Young (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Park, Tae-Soon (Department of Cosmeceutical Science, Daegu Haany University)
  • 안봉전 (대구한의대학교 화장품약리학과) ;
  • 조영제 (상주대학교 식품공학과) ;
  • 손준호 (대구한의대학교 화장품약리학과) ;
  • 박정미 (대구한의대학교 화장품약리학과) ;
  • 이진영 (대구한의대학교 화장품약리학과) ;
  • 박태순 (대구한의대학교 화장품약리학과)
  • Published : 2006.06.01
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Abstract

Biological activities and application of Prunus sargentii Rehder were investigated. In the physiological activities, the electron donating ability (EDA) of ethanol extracts of Prunus sargentii Rehder was 85% in 100 ppm. SOD-like activity was inhibition about 50% in 1,000 ppm, it was gradual increased. As inhibitory effect of xanthine oxidase, it was more than 70% in 1,000 ppm and inhibitory effect of tyrosinase was a little low as 20% below 1,000 ppm.

본 연구는 화피의 효소학적 생리활성을 검토하였다. 효소학적 생리활성 실험에서의 전자 공여능은 100 ppm에서 에탄올추출물은 85% 이상의 효능을 나타냈으며, SOD-유사활성능은 1,000 ppm에서 50%의 활성을 나타내었으며, 농도가 증가함에 따라 유의적인 차이를 나타내었다. Xanthine oxidase의 저해활성을 관찰한 결과 1,000 ppm에서는 70% 이상으로 저해효과를 나타내었다. 피부 미백과 관련 있는 tyrosinase 저해효과를 측정한 결과 1,000 ppm 이하의 농도에서 20%의 저해효과를 나타내었다.

Keywords

References

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