DOI QR코드

DOI QR Code

Quantitative Changes in Phenolic Compounds of Safflower (Carthamus tinctorius L.) Seeds during Growth and Processing

  • Kim, Eun-Ok (Department of Food Science and Nutrition, Catholic University of Daegu) ;
  • Lee, Jun-Young (Department of Food Science and Nutrition, Catholic University of Daegu) ;
  • Choi, Sang-Won (Department of Food Science and Nutrition, Catholic University of Daegu)
  • Published : 2006.12.01

Abstract

Phenolic compounds in safflower seeds were recently found to stimulate bone formation and increase plasma HDL cholesterol levels in estrogen deficient rats, and to inhibit melanin synthesis. Nine phenolic compounds: $N-feruloylserotonin-5-O-{\beta}-D-glucoside,\;8'-hydroxyarctigenin-4'-O-{\beta}-D-glucoside,\;luteolin-7-O-{\beta}-D-glucoside$, N-(p-coumaroyl)serotonin, N-feruloylserotonin, 8'-hydroxy arctigenin (HAG), luteolin (LT), $acacetin-7-O-{\beta}-D-glucuronide$ (ATG) and acacetin (AT), were quantified by HPLC in safflower (Carthamus tinctorius L.) seeds during growth and processing. During growth, levels of the nine phenolic compounds in the seeds increased progressively with increasing growth stages, reached a maximum on July 30 (42nd day after flowering), and then remained relatively constant. During the roasting process, levels of phenolic compounds, except HAG, LT and AT, generally decreased with increased roasting temperature and time, whereas those of HAG, LT and AT increased progressively with increased roasting temperature and time. During the steaming process, levels of other phenolic compounds except HAG and AT generally tended to increase with increased steaming time, whereas those of HAG and AT were scarcely changed. During the microwave treatment, quantitative changes of phenolic compounds were similar to the roasting process, although there were some differences in levels of phenolic compounds between two heat treatments. These results suggest that the steamed safflower seeds after harvesting on late July may be useful as potential dietary supplement source of phenolic compounds for prevention of several pathological disorders, such as atherosclerosis and osteoporosis and aging.

Keywords

References

  1. An DK, Yuk CS. 1975. Present medical plants. In Safflower. Komoon Publishers, Seoul, Korea. p 358-359
  2. Lee CB. 1980. Picture book of Korean plants. In Safflower. Baekyang Publishers, Seoul, Korea. p 779
  3. Park YH, Park HK, Lee HJ, Park SM, Choi SW, Lee WJ. 2002. Phytoestrogen-induced phosphorylation of MAP kinase in osteoblasts is mediated by membrane estrogen receptor. Korean J Physiol Pharmacol 6: 165-169
  4. Kim HJ, Bae YC, Park RW, Choi SW, Cho SH, Choi YS, Lee WJ. 2002. Bone protecting effect of safflower seeds in ovariectomized rats. Calcif Tissue Int 71: 88-94 https://doi.org/10.1007/s00223-001-1080-4
  5. Cho SH, Lee HL, Kim TH, Choi SW, Lee WJ, Choi YS. 2004. Effects of defatted safflower seed extract and phenolic compounds in diet on plasma and liver lipid in ovariectomized rats fed high-cholesterol diets. J Nutr Sci Vitaminol 50: 32-37 https://doi.org/10.3177/jnsv.50.32
  6. Zhang HL, Nagatsu A, Watanabe T, Sakakibara J, Okuyama H. 1997. Antioxidative compounds isolated from safflower (Carthamus tinctorious L.) oil cake. Chem Pharm Bull 45: 1910-1914 https://doi.org/10.1248/cpb.45.1910
  7. Kang GH, Chang EJ, Choi SW. 1999. Antioxidative activity of phenolic compounds in roasted safflower seeds. J Korean Soc Food Sci Nutr 4: 221-225
  8. Roh JS, Sun WS, Oh SU, Lee JI, Oh WT, Kim JH. 1999. In vitro antioxidant activity of safflower (Carthamus tinctorious L.) seeds. Food Sci Biotechnol 8: 88-92
  9. Kawashima S, Hayashi M, Takii T, Kimura H, Ahang HL, Nagatsu A, Sakakibara J, Murata K, Oomoto Y, Onozaki K. 1998. Serotonin derivative, N-(p-coumaroyl)serotonin, inhibits the production of TNF-${\alpha}$, IL-1${\alpha}$, IL-I${\beta}$, and IL-6 by endotoxin stimulated human blood monocytes. J Interferon Cytokine Res 18: 423-428 https://doi.org/10.1089/jir.1998.18.423
  10. Bae SJ, Shim SM, Park YJ, Lee JY, Chang EY, Choi SW. 2002. Cytotoxicity of phenolic compounds isolated from seeds of safflower (Carthamus tinctorius L.) on cancer cell lines. Food Sci Biotechnol 11: 140-146
  11. Takii T, Hayashi M, Hiroma H, Chiba T, Kawashima S, Zhang HL, Nagatsu A, Sakakibara J, Onozaki K. 1999. Serotonin derivative, N-(p-coumaroyl)serotonin, isolated from safflower (Carthamus tinctorious L.) oil cake augments the proliferation of normal human and mouse fibroblasts in synergy with basic fibroblast growth factor (${\beta}$FGF) of epidermal growth factor (EGF). J Biochem 125: 910-915 https://doi.org/10.1093/oxfordjournals.jbchem.a022368
  12. Roh JS, Han JY, Kim JH, Hwang JK. 2004. Inhibitory effects of active compounds isolated from safflower (Carthamus tinctorius L.) seeds for melanogenesis. Biol Pharm Bull 27: 1976-1978 https://doi.org/10.1248/bpb.27.1976
  13. Kim MJ, Kim JY, Choi SW, Hong JT, Yoon KS. 2004. Anti-wrinkle effect of safflower (Carthamus tinctorius) seed extract (I). J Soc Cosmet Scientists Korea 30: 15-22
  14. Kim MJ, Kim JY, Choi SW, Hong JT, Yoon KS. 2004. Anti-wrinkle effect of safflower (Carthamus tinctorius) seed extract (II). J Soc Cosmet Scientists Korea 30: 449- 456
  15. Palter R, Lundin RE, Haddon WF. 1972. A cathartic lignan glycoside isolated from Carthamus tinctorus. Phytochemistry 11: 2871-2874 https://doi.org/10.1016/S0031-9422(00)86527-9
  16. Sakamura S, Terayama Y, Kawakatsu S, Ichihara A, Saito H. 1978. Conjugated serotonins related to cathartic activity in safflower seeds (Carthamus tinctorious L.). Agric Biol Chem 42: 1805-1806 https://doi.org/10.1271/bbb1961.42.1805
  17. Naczk M, Shahidi F. 2003. Phenolic compounds in plant foods: chemistry and health benefits. Nutraceuticals & Food 8: 200-218 https://doi.org/10.3746/jfn.2003.8.2.200
  18. Macheix JJ, Fleurit A, Billot J. 1990. Fruit Phenolics.  CRC Press, Boca Raton. p 237-245
  19. Lee JY, Park KS, Choi SW. 2004. Changes in flavonoid contents of safflower leaf during growth and processing. J Food Sci Nutr 10: 1-5 https://doi.org/10.3746/jfn.2005.10.1.001
  20. Yoshida H, Takagi S. 1997. Effects of seed roasting temperature and time of the quality characteristics of sesame (Sesamum indicum) oil. J Sci Food Agric 75: 19-26 https://doi.org/10.1002/(SICI)1097-0010(199709)75:1<19::AID-JSFA830>3.0.CO;2-C
  21. Moreau RA, Hicks KB, Powell MJ. 1999. Effect of heat pretreatment on the yield and composition of oil extracted from corn fiber. J Agric Food Chem 47: 2869-2871 https://doi.org/10.1021/jf981186c
  22. Kim IH, Kim CJ, You JM, Lee KW, Kim CT, Chung SH, Tae BS. 2002. Effect of roasting temperature and time on the chemical composition of rice germ oil. J Am Oil Chem Soc 79: 413-418 https://doi.org/10.1007/s11746-002-0498-2
  23. Kadlec P, Skulinova M, Kaasova J, Bubnik Z, Pour V, Dostalova J, Valentova H, Hosnedl V. 2003. Changes in composition of pea during germination, microwave treatment and drying. Food Sci Biotechnol 12: 213-218
  24. Lee KT, Lee JY, Kwon YJ, Yu F, Choi SW. 2004. Changes in functional constituents of grape (Vitis vinifera) seed by different heat pretreatments. J Food Sci Nutr 9: 144-149 https://doi.org/10.3746/jfn.2004.9.2.144
  25. Kim EO, Oh JH, Lee SK, Lee JY, Choi SW. 2006. Antioxidant property and quantification of phenolic compounds from safflower (Carthamus tinctorius L.) seeds. Food Sci Biotechnol (accepted)
  26. Sakamura A, Terayama Y, Kawakatsu S, Ichihara A, Saito H. 1980. Conjugated serotonins and phenolic constituents in safflower seed (Carthamus tinctorious L.). Agric Biol Chem 44: 2951-2954 https://doi.org/10.1271/bbb1961.44.2951
  27. Chung SH, Moon KD, Kim JK, Seong JH, Sohn TH. 1994. Changes of chemical components in persimmon leaves during growth for processing persimmon leaves tea. Korean J Food Sci Technol 26: 141-146
  28. Iwasa K. 1975. Method chemical analysis of green tea. Jpn Agr Res Quart 9: 161-169
  29. Ko YS, Lee IS. 1985. A study on the changes of the components in the steaming and roasting green tea after heat treatments according to time. J Korean Soc Home Economic 23: 29-36

Cited by

  1. Effects of feeding roasted safflower seeds (variety IL-111) and fish oil on dry matter intake, performance and milk fatty acid profiles in dairy cattle vol.96, pp.3, 2012, https://doi.org/10.1111/j.1439-0396.2011.01165.x
  2. Safflower seeds in corn silage and alfalfa hay based early lactation diets: A practice within an optimum forage choice vol.155, pp.1, 2010, https://doi.org/10.1016/j.anifeedsci.2009.09.014
  3. Characteristics of Specialty Natural Micronutrients in Certain Oilseeds and Oils: Plastochromanol-8, Resveratrol, 5-Hydroxytryptamine Phenylpropanoid Amides, Lanosterol, Ergosterol and Cyclolinopeptides vol.93, pp.2, 2016, https://doi.org/10.1007/s11746-015-2771-8
  4. 8-hydroxyarctigenin isolated from safflower sprouts inhibits melanogenesis of melan-a cells and light quality during the sprout growth determines the compound yield vol.55, pp.2, 2014, https://doi.org/10.1007/s13580-014-0120-8
  5. Analysis of Functional Constituents in Mulberry (Morus alba L.) Twigs by Different Cultivars, Producing Areas, and Heat Processings vol.18, pp.4, 2013, https://doi.org/10.3746/pnf.2013.18.4.256
  6. Quantitative Changes of Polyphenolic Compounds in Mulberry (Morus alba L.) Leaves in Relation to Varieties, Harvest Period, and Heat Processing vol.17, pp.4, 2012, https://doi.org/10.3746/pnf.2012.17.4.280
  7. 홍화(Carthamus tinctorius L.)씨와 발아홍화씨의 화학성분 비교 vol.37, pp.9, 2006, https://doi.org/10.3746/jkfn.2008.37.9.1162
  8. Preparation of High Quality Safflower (Carthamus tinctorius L.) Seed Extract by High-Pressure Extraction Process vol.14, pp.4, 2006, https://doi.org/10.3746/jfn.2009.14.4.373
  9. Impact of Betaine Under Salinity on Accumulation of Phenolic Compounds in Safflower (Carthamus tinctorius L.) Sprouts vol.16, pp.5, 2006, https://doi.org/10.1177/1934578x211015090
  10. Recovery of phytochemical from three safflower ( Carthamus tinctorius L.) by‐products: Antioxidant properties, protective effect of human erythrocytes and profile by UPLC‐DAD‐MS vol.45, pp.9, 2006, https://doi.org/10.1111/jfpp.15765
  11. LC-MS/MS fingerprint and simultaneous quantification of bioactive compounds in safflower petals (Carthamus tinctorius L.) vol.171, pp.None, 2006, https://doi.org/10.1016/j.microc.2021.106850