Journal of Nutrition and Health

The Korean Nutrition Society (한국영양학회)
권호 표지

Association between Plasma Tocopherol Levels and Related Factors in Middle-Aged Korean Men

한국 성인 남자의 혈장 Tocopherol 수준과 관련 요인 분석

  • Kim, Kyung-Ja (Department of Food and Nutrition, Hannam University) ;
  • Lee, Hye-Jin (Department of Food and Nutrition, Hannam University) ;
  • Park, Yoo-Kyoung (Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University) ;
  • Kang, Myung-Hee (Department of Food and Nutrition, Hannam University)
  • 김경자 (한남대학교 생명나노과학대학 식품영양학과) ;
  • 이혜진 (한남대학교 생명나노과학대학 식품영양학과) ;
  • 박유경 (경희대학교 동서의학대학원 의학영양학과) ;
  • 강명희 (한남대학교 생명나노과학대학 식품영양학과)
  • Published : 2006.12.31
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Abstract

Vitamin E in the body system plays an important role in preventing chronic diseases by decreasing the oxidative stress by free-radicals. However, there are not enough researches on analyzing the primary factors affecting vitamin E levels in the blood in Korean adults. Therefore, the purpose of this research was to examine blood tocopherol levels and the primary factors affecting the status. A complete lifestyle survey was performed on 314 Korean adult men and surveyed their smoking, drinking and exercising habits. The average plasma level of ${\alpha}-\;and\;{\gamma}-tocopherol$ showed similar mutual relations with plasma total cholesterol (TC), triglyceride (TG), or low density lipoprotein cholesterol (LDL-C) levels (p<0.001). Plasma ${\alpha}-tocopherol$ level of the subjects did not show any difference as smoking, drinking and exercising habits changed. However, ${\gamma}-tocopherol$ per TG showed much lower figure in smokers than non smokers (p < 0.05). Amongst diet factors, plasma ${\alpha}-tocopherol$ level showed negative correlations with Vitamin E intake, while ${\gamma}-tocopherol$ level showed positive correlations with Vitamin E intake. Erythrocyte superoxide dismutase (SOD) activity and plasma tocopherol showed negative correlations, and catalase activity and plasma ${\alpha}-tocopherol$ showed positive correlationship. The level of cell DNA damage of Iymphocyte and plasma ${\alpha}-\;or\;{\gamma}-tocopherol$ showed negative correlations. As a result of this research, the factors that affect Korean adult men's plasma ${\alpha}-tocopherol$ level are plasma TG, LDL-C and cell DNA damage in Iymphocyte, while the factors that affect ${\gamma}-tocopherol$ level are plasma TG, LDL-C and vitamin E intake based on multiple regression analysis. These findings implies that the level of different types of tocopherol depends on slightly different factors. A further research is needed on the factors involved in the differentiation of the types of tocopherol.

Keywords

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