Journal of The Korean Society of Clinical Toxicology (대한임상독성학회지)
- Volume 4 Issue 2
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- Pages.147-150
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- 2006
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- 1738-1320(pISSN)
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- 2508-6332(eISSN)
Neurotoxic Shellfish Poisoning after Ingesting Whelk
신경독성 조개류 중독 3례
- Ko, Young-Gil (Departments of Emergency Medicine, Inje University Seoul Paik Hospital) ;
- Ahn, Ji-Young (Departments of Emergency Medicine, Inje University Seoul Paik Hospital) ;
- Ryu, Seok-Yong (Departments of Emergency Medicine, Inje University Sang-Gae Paik Hospital) ;
- Lee, Sang-Lae (Departments of Emergency Medicine, Inje University Sang-Gae Paik Hospital) ;
- Cho, Suk-Jin (Departments of Emergency Medicine, Inje University Sang-Gae Paik Hospital) ;
- Kim, Mi-Ran (Departments of Emergency Medicine, Inje University Pusan Paik Hospital)
- 고영길 (인제대학교 의과대학 서울병병원 응급의학과) ;
- 안지영 (인제대학교 의과대학 서울병병원 응급의학과) ;
- 류석용 (상계백병원 응급의학과) ;
- 이상래 (상계백병원 응급의학과) ;
- 조석진 (상계백병원 응급의학과) ;
- 김미란 (부산백병원 응급의학과)
- Published : 2006.12.31
Abstract
Neurotoxic shellfish poisoning (NSP) can result from eating filter-feeding shellfish carrying brevetoxins produced by the marine dinoflagellate Krenia brevis (formally Gymnodinium breve). Brevetoxins enhance sodium entry into cells via voltage-sensitive sodium channels and have an excitatory effect. The incubation period is three hours (range 15 minutes-18 hours). NSP is characterized by gastroenteritis combined with neurologic symptoms. Gastrointestinal (GI) symptoms include abdominal pain, nausea, diarrhea and burning pain in the rectum. Neurologic symptoms are paresthesia, reversal of hot and cold temperature sensation, myalgia, headache, vertigo, and ataxia. Other symptoms may include malaise, tremor, dysphagia, bradycardia, decreased reflexes, dilated pupils, seizure, and coma. The health problem caused by K. breviscan be associated with a red tide bloom. We encountered 3 cases of neurotoxic shellfish poisoning. They all presented with GI and neurologic symptoms andrecovered after conservative treatment.