Effects of Hangbisan, an Oriental Medicine, on Body Weight Gain in Diet-Induced Obese (DID) rats

  • Chae, Myoung-Hee (Department of Food and Nutrition and the Human Ecology Research Institute, Chonnam National University) ;
  • No, Jin-Gu (Baek-du Oriental Medicine Center) ;
  • Jhon, Deok-Young (Department of Food and Nutrition and the Human Ecology Research Institute, Chonnam National University)
  • Published : 2006.02.28

Abstract

This study was designed to determine possible weight loss effects of Hangbisan, an oriental medicine, on Sprague-Dawley (SD) rats. SD rats that were fed a high-fat diet for 6 weeks to induce obesity and subsequently fed with a basic diet containing 10%(w/w) Hangbisan or 10%(w/w) cellulose for 8 weeks. The Hangbisan fed rats demonstrated a significantly (p<0.05) reduced weight gain compared to the cellulose fed rats as well as a reduced level of plasma cholesterol and triglycerides and an increased level of (HDL)-cholesterol. These results suggest that dietary Hangbisan has an anti-obesity effect in the high-fat diet-induced obesity (DIG) rat and therefore a potential use as an anti-obesity agent in the application of oriental medicine compounds.

Keywords

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