The Korean Journal of Pain

The Korean Pain Society (대한통증학회)
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Naproxen-induced Immune Thrombocytopenia -A case report-

Naproxen에 의해 유발된 중증 면역성 혈소판 감소증 -증례보고-

  • Kim, Cheol Kun (Department of Anesthesiology and Pain Medicine, Presbyterian Medical Center) ;
  • Jang, In Su (Department of Anesthesiology and Pain Medicine, Presbyterian Medical Center) ;
  • Lee, Jun Hak (Department of Anesthesiology and Pain Medicine, Presbyterian Medical Center) ;
  • Kwon, Young Eun (Department of Anesthesiology and Pain Medicine, Presbyterian Medical Center) ;
  • Park, Sang Chul (Department of Anesthesiology and Pain Medicine, Presbyterian Medical Center)
  • 김철근 (전주예수병원 마취통증의학과) ;
  • 장인수 (전주예수병원 마취통증의학과) ;
  • 이준학 (전주예수병원 마취통증의학과) ;
  • 권영은 (전주예수병원 마취통증의학과) ;
  • 박상철 (전주예수병원 마취통증의학과)
  • Received : 2006.05.08
  • Accepted : 2006.09.08
  • Published : 2006.12.30
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Abstract

Hundreds of drugs have been implicated as the causes of antibody-mediated thrombocytopenia. Naproxen is a commonly used nonsteroidal anti-inflammatory drug, and it is generally considered to be safe with few hematological side effects such as thrombocytopenia. In this case, severe thrombocytopenia associated with petechia and epistaxis appeared after initiation of naproxen therapy in the 59-year-old man. We report here on a case of severe thrombocytopenia that was recognized at 10 days after the use of naproxen, and the patient rapidly recovered to a normal platelet count without bleeding symptoms or any complications, although immunoglobulin or steroid was not used.

Keywords

References

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