A Case of Recurrent Aggressive Angiomyxoma of the Vulva

외음부에 재발한 공격성 혈관점액종 1예

Shin, Hyun-Mi;Yang, Yong-Jae;Lee, Keun-Ho;Lee, Hee-Joong;Jeon, Chung-Rha;Shin, Ok-Ran;Koo, Young-Mi;Lee, Jin-Woo;Park, Tae-Chul
신현미;양용재;이근호;이희중;전청라;신옥란;구영미;이진우;박태철

  • Published : 20060500

Abstract

Aggressive angiomyxoma (AAM) is an extremely uncommon neoplasm of the female genitalia. This tumor arises from soft tissue of the perineum, and affects predominantly young women. Although surgical excision with wide tumor-free margins may be necessary to obtain a complete cure, some of patients experience local recurrences because of the infiltrative nature of this tumor. We experienced a case of recurrent huge AAM on the right vulva in 29-year-old woman and reported it with a brief review of literature.

저자들은 우측 외음부에 재발한 부드럽고, 압통이 없는, 거대한 돌출성 종괴를 주소로 내원한 29세 여성에서, 조직학적으로 공격성 혈관점액종으로 진단되어 성공적으로 수술한 1예를 경험하여 문헌과 함께 보고하는 바이다.

Keywords

References

  1. Yalinkaya A, Askar I, Bayhan G, Kilinc N, Yayla M. Aggressive angiomyxoma of the female pelvis and the labium. Acta Obstet Gynecol Scand 2003; 82(3): 298-301 https://doi.org/10.1034/j.1600-0412.2003.00113.x
  2. Steeper TA, Rosai J. Aggressive angiomyxoma of the female pelvis and perineum. Report of nine cases of a distinctive type of gynecologic soft-tissue neoplasm. Am J Surg Pathol 1983; 7: 463-75 https://doi.org/10.1097/00000478-198307000-00009
  3. Abdel-Nabi AG, Sharabati B. Aggressive angiomyxoma of the vulva. J Obstet Gynaecol 1997; 17(3): 317 https://doi.org/10.1080/01443619750113465
  4. Nucci MR, Flecher CDM. Vulvovaginal soft tissue tumours: update and review. Histopathology 2000; 36: 97-108 https://doi.org/10.1046/j.1365-2559.2000.00865.x
  5. 김성주, 김창모, 김범, 장기택, 강정배, 장봉림 등. 증례보고: 질에 발생한 공격성 혈관 점액종 1예. 대한산부회지 2001; 44(7): 1350-2.
  6. Gungor T, Zengeroglu S, Kaleli A, Kuzey GM. Aggressive angiomyxoma of the vulva and vagina. A common problem: misdiagnosis. Eur J Obstet Gynecol Reprod Biol 2004 15; 112(1): 114-6 https://doi.org/10.1016/0028-2243(83)90180-6
  7. Behranwala KA, Latifaj B, Blake P, Barton DP, Shepherd JH, Thomas JM. Vulvar soft tissue tumors. Int J Gynecol Cancer 2004; 14(1): 94-9 https://doi.org/10.1111/j.1048-891X.2004.14946.x
  8. 양영민, 조영리, 안광준, 김항진, 김익수. 증례보고: 좌골직장와에 발생한 공격성 혈관점액종. 대한산부회지 2003; 46(8): 1567- 70.
  9. Nakamura T, Miura K, Maruo Y, Sunayama K, Maruyama K, Kashiwabara H, et al. Aggressive angiomyxoma of the perineum originating from the rectal wall. J Gastroentrol 2002; 37: 303-8 https://doi.org/10.1007/s005350200040
  10. Skalova A, Michal M, Hus K, Zamecnik M, Leivo I. Aggressive angiomyxoma of the pelvioperineal region. Immunohistological study of seven cases. Am J Dermatopathol 1993; 15: 446-51 https://doi.org/10.1097/00000372-199310000-00006
  11. Granter SR, Nucci MR Fletcher CD. Aggressive angiomyxoma: reappraisal of relationship to angiomyofibroblastoma in a series of 16 cases. Histopathology 1997; 30: 3-10 https://doi.org/10.1046/j.1365-2559.1997.d01-556.x
  12. Behranwala KA, Thomas JM. Aggressive angiomyxoma: a distint clinical entity. Eur J Surg Oncol 2003; 29: 558-63
  13. Behranwala KA, Clark MA, Thomas JM. Soft-tissue tumor of the perineum. Eur J Surg Oncol 2002; 28: 437-42 https://doi.org/10.1053/ejso.2002.1267
  14. Chan IM, Hon E, Ngai SW, Ng TY, Wong LC. Aggressive angiomyxoma in female: is radical resection the only option? Acta Obstet Gynecol Scand 2000; 79: 216-20 https://doi.org/10.1080/j.1600-0412.2000.079003216.x
  15. Begin LR, Clement PB, Kirk ME, Jothy S, McCaughey WT, Ferenczy A. Aggressive angiomyxoma of pelvic soft parts: a clinicopathologic study of nine cases. Hum Pathol 1985; 16: 621-8 https://doi.org/10.1016/S0046-8177(85)80112-X
  16. Wolf CA, Kurzeja R, Fietze E, Buscher U. Aggressive angiomyxoma of the female perineum in pregnancy. Acta Obstet Gynecol Scand 2003; 82(5): 484-5 https://doi.org/10.1034/j.1600-0412.2003.00160.x
  17. Shinohara N, Nonomura K, Ishikawa S, Seki H, Koyanagi T. Medical management of recurrent aggressive angiomyxoma with gonadotropinreleasing hormone agonist. Int J Urol 2004; 11(6): 432-5 https://doi.org/10.1111/j.1442-2042.2004.00816.x
  18. Poirier M, Fraser R, Meterissian S. Case 1. Aggressive angiomyxoma of the pelvis: response to luteinizing hormone-releasing hormone agonist. J Clin Oncol 2003; 21(18): 3535-6 https://doi.org/10.1200/JCO.2003.10.174
  19. Amezcua CA, Begley SJ, Mata N, Felix JC, Ballard CA. Aggressive angiomyxoma of the female genital tract: a clinicopathologic and immunohistochemical study of 12 cases. Int J Gynecol Cancer 2005; 15(1): 140-5 https://doi.org/10.1111/j.1048-891x.2005.15015.x