12주 체중감량프로그램이 비만여중생의 호모시스테인과 C-반응성단백질에 미치는 효과

The effect of 12-week resistance training on muscle buffering capacity by single fiber dissection

김태운;김현준;박찬호;박태곤;김종원;양영옥
Kim, Tae-Un;Kim, Hyeon-Jun;Park, Chan-Ho;Park, Tae-Gon;Kim, Jong-Won;Yang, Yeong-Ok

  • 발행 : 20060000

초록

12주 체중감량프로그램이 비만여중생의 호모시스테인과 C-반응성단백질에 미치는 효과. 운동과학, 제15권 제4호, 309-317, 2006. 본 연구의 목적은 비만여중생에게 걷기운동과 행동수정을 포함한 체중감량 프로그램을 12주간 실시하여 프로그램 실시에 따른 호모시스테인(Hcy)과 C-반응성단백질(CRP)의 변화를 비교 분석하고, 프로그램 실시 전과 후의 신체구성 및 전통적 심혈관질환 위험인자와 Hcy 및 CRP 간의 관련성을 분석하는 것이었다. 연구의 대상자는 연령과 성별에 따른 체질량지수 백분위 수 95 이상인 비만여중생 40명을 프로그램에 참여하는 실험군에 19명, 대조군에 21명을 무선배치 하였다. 연구결과 집단내 변화에서 Hcy와 CRP는 프로그램 실시 후 변화가 나타나지 않았다. 집단간 변화량에 대한 차이비교에서 CRP는 실험군과 대조군 간에 차이가 있었으나 Hcy는 차이가 없었다. 또한 CRP는 프로그램실시 전에는 체지방량 및 수축기혈압과 양의 상관관계를, CRP 변화량은 BMI 변화량과 양의 상관관계를 나타냈다. 그렇지만 Hcy는 신체구성 및 전통적 심혈관질환 위험인자와 아무런 관련성이 없는 것으로 나타났다. 이상의 연구결과와 최근의 선행연구 결과들을 종합해 볼 때 체중감량 프로그램이 CRP의 변화에 긍정적인 효과를 나타내 선행연구와 비슷한 결과를 얻었지만, Hcy의 변화에는 영향을 미치지 못함을 확인하였는데 이는 아마도 Hcy의 변화에는 체중감량 이외에 아직 밝혀지지 않은 다른 대사적요인들이 복합적으로 영향을 미치고 있음을 시사함으로 추후 이에 관련된 잘 통제된 후속 연구가 더 필요할 것으로 생각된다.

Effects of a 12-week weight-loss program on homocysteine and C-reactive protein in obese middle school girls. Exercise Science, 15(4), 309-317, 2006. The aim of this study was to determine the effect of 12 weeks weight-loss program including walking and behavior modification on homocysteine (Hcy), C-reactive protein (CRP), and to analyze association between the changes of body composition, traditional cardiovascular disease (CVD) risk factors and the changes of Hcy and CRP in obese middle school girls. Forty participants (body mass index[BMI]≥95th percentile) were randomly allocated to experimental group (EG, n=19) and control group (CG, n=21). There were no changes on Hcy and CRP levels in the experimental group after intervention. But the change of CRP level was significant difference between groups after intervention (p<.05). Also there was significant correlation with between CRP and fat mass (r=0.35), systolic blood pressure (r=0.38) at base line, and the change of CRP was correlated with the change of BMI (r=0.46). However Hcy was not any relationship with body composition and CVD risk factors. In conclusion, weight-loss program can be useful intervention for the improvement on body composition, CVD risk factors and CRP in obese adolescent girls. However there was no change in Hcy; therefore there may be involved in unknown metabolic factors which are associated with the change of Hcy.

키워드

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