A Cross Section Study : Hot Flush of Postmenopausal Women Who Participated in a Clinical Trial

안면홍조에 대한 임상시험 참가자의 증상 발현 양상에 관한 연구

  • Roh, Jin-Ju (Dept. of Obstetrics & Gynecology, College of Oriental Medicine, Dongguk University) ;
  • Jung, Su-Kyoung (Dept. of Obstetrics & Gynecology, College of Oriental Medicine, Dongguk University) ;
  • Seung, Jun-Ho (Dept. of Obstetrics & Gynecology, College of Oriental Medicine, Dongguk University) ;
  • Lee, Seung-Deok (Dept. of Acupuncture & Moxibution, College of Oriental Medicine, Dongguk University) ;
  • Ahn, Hong-Yup (Dept. of Statistics, College of Science, Dongguk University) ;
  • Oh, Dal-Seok (Dept. of Medical R&D, Korea Institute of Oriental Medicine) ;
  • Choi, Sun-Mi (Dept. of Medical R&D, Korea Institute of Oriental Medicine) ;
  • Kim, Dong-Il (Dept. of Obstetrics & Gynecology, College of Oriental Medicine, Dongguk University)
  • 노진주 (동국대학교 한의과대학 한방부인과학교실) ;
  • 정수경 (동국대학교 한의과대학 한방부인과학교실) ;
  • 성준호 (동국대학교 한의과대학 한방부인과학교실) ;
  • 이승덕 (동국대학교 한의과대학 침구학교실) ;
  • 안홍엽 (동국대학교 이과대학 통계학교실) ;
  • 오달석 (한국한의학연구원 의료연구부) ;
  • 최선미 (한국한의학연구원 의료연구부) ;
  • 김동일 (동국대학교 한의과대학 한방부인과학교실)
  • Published : 2006.11.30

Abstract

Purpose : To identify factors related to the severity and frequency of hot flush of postmenopausal women who participated in a clinical trial. Methods : A cross-section study of 34 postmenopausal women between 40 and 60 years of age was done. VAS(visual analog scale) was used to evaluate the hot flush degree. Statistical analysis was performed with multiple linear regression analysis. Results : Hot flush VAS was proportional to the percent body fat with 1.467 regression coefficient (p-value= 0.010). It implies that the symptom of hot flush becomes worse as the percent body fat increases. Some hormones also have effects on hot flush. We found that LH might cause increment of hot flush VAS(i.e., the corresponding regression coefficient is 0.912). Sasang constitution was not relevant to the hot flush degree. Hot flush VAS seemed to increase as the vascular aging degree by SA-2000 getting worse, but it was not statistically significant (p-value= 0.594). Conclusion : This study is a part of a prospective clinical trial. For more accurate result, larger-scale cross-section study or clinical trial are necessary.

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