The Journal of Korean Obstetrics and Gynecology (대한한방부인과학회지)

The Society of Korean Medicine Obstetrics and Gynecology (대한한방부인과학회)
권호 표지

Effects of Paljin-tang on Surgically Induced Endometriosis in Rats

팔진탕(八珍湯)이 자궁내막증(子宮內膜症)을 유발한 흰쥐에 미치는 영향

  • Lim, Eun-Mee (Dept. of Gynecology, College of Oriental Medicine, Kyungwon University) ;
  • Kwon, Ki-Rok (Dept. of Acupuncture and Moxibustion, College of Oriental Medicine, Sangji University) ;
  • Lee, Mi-Jumg (Dept. of Gynecology, College of Oriental Medicine, Kyungwon University)
  • 임은미 (경원대학교 한의과대학 부인과학교실) ;
  • 권기록 (상지대학교 한의과대학 침구학교실) ;
  • 이미정 (경원대학교 한의과대학 부인과학교실)
  • Published : 2006.08.31
Download PDF
⟨ Previous Next ⟩

Abstract

Purpose : This study examined effects of Paljin-tang on endometriosis. Methods : Sugically induced endometriosis in rats were given an oral dose of Paljin-tang for 40 days. The size of the ectopic uterine implants at the serosal wall and the concentration of progesterone, estradiol, tumor necrosis factor(TNF)-${\alpha}$ and interleukin(IL)-2, IL-4, IL-6, and IL-10 in the blood were examined and compared with the control group. Results : The size of the ectopic uterine implants in the experimental group was much smaller than of that in the control group. The concentration of estradiol was significantly lower in the experimental group than in the control group. The TNF-${\alpha}$, IL-4, IL-6 levels was significantly lower in the experimental group than the control group and IL-10 level was higher in the experimental group than the control group. The progesterone, IL-2 levels were similar in the experimental and control groups. Conclusion : These results indicate that Paljin-tang reduces the size of ectopic uterine implants at the serosal wall and inhibits the growth of ectopic uterine implants. This suggests that Paljin-tang is an effective treatment for endometriosis.

Keywords