Korean Journal of Community Nutrition (대한지역사회영양학회지)

The Korean Society of Community Nutrition (대한지역사회영양학회)
권호 표지

Obesity Indices and Plasma Total Antioxidant Status in Hypertensive Elderly Living in Ulsan Area

울산 지역 고혈압 노인의 비만 지표 및 혈중 총항산화도

  • Kim Jung-Hee (Department of Food and Nutrition, Seoul Women's University) ;
  • Kim Mi-Joung (Department of Food and Nutrition, Seoul Women's University) ;
  • Kwak Ho-Kyung (Department of Home Economics, Korea National Open University)
  • 김정희 (서울여자대학교 식품영양학과) ;
  • 김미정 (서울여자대학교 식품영양학과) ;
  • 곽호경 (한국방송통신대학교 가정학과)
  • Published : 2006.04.01
Download PDF
⟨ Previous Next ⟩

Abstract

The role of free radicals in the progression of many diseases and aging has been given a great attention and total antioxidant status (TAS) has shown to be reduced with aging. The incidence of hypertension has shown to be relatively high in the aged population, and it is known to be associated with increased obesity and oxidative stress. The aim of this study was to examine the obesity indices and the total antioxidant status in hypertensive elderly (64y$\alpha$-tocopherol, $\beta$-carotene and ascorbic acid did not show their significant correlations with TAS. These results showed that the hypertensive elderly are prone to be obese and to have increased TAS. Due to unknown factors affecting TAS values, measurement of plasma TAS as a sole indicator of total antioxidant capacity is limited to fully understanding changes in the body's free radical trapping power. However, the results from the current study may suggest that hypertension and/or obesity might increase oxidative stress, followed by increased the body's total antioxidant defense system.

Keywords

References

  1. 김현승(1993): 노인성 고혈압의 최신지견. 대한의사협회지 36(12): 1406-1410
  2. 1999 World health organization - International society of hypertension guidelines for the management of hypertension. Guidelines subcommittee. J Hypertens 17: 151-183
  3. Korean National Statistical Office (2003): The cause of death statistics 2002 (deaths and death rates)
  4. Ames BN, Shigenaga MK, Hagen TM (1993): Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci U S A 90: 7915-22
  5. Andriollo-Sanchez M, Hininger-Favier I, Meunier N, Venneria E, O'Connor JM, Maiani G, Coudray C, Roussel AM (2005): Agerelated oxidative stress and antioxidant parameters in middle-aged and older European subjects: the ZENITH study. Eur J Clin Nut 59: S58-62 https://doi.org/10.1038/sj.ejcn.1602300
  6. Baynes JW (1991): Role of oxidative stress in development of complications in diabetes. Diabetes 40: 405-12 https://doi.org/10.2337/diabetes.40.4.405
  7. Bieri JG, Tolliver TJ, Catignani L (1979): Simultaneous determination of ${\alpha}-tocopherol$ and retinol in plasma or red cells by high pressure liquid chromatography. Am J Clin Nutr 32: 2143-2149 https://doi.org/10.1093/ajcn/32.10.2143
  8. Bieri JG, Brown ED, Smith JC (1985): Determination of individual carotenoid in human plasma by high performance liquid chromatography. J Liq Chrom 8(3): 474-484
  9. Buijsse B, Feskens EJ, Schlettwein-Gsell D, Ferry M, Kok FJ, Kromhout D, de Groot LC (2005): Plasma carotene and ${\alpha}-tocopherol$ in relation to 10-y all-cause and cause-specific mortality in European elderly: the Survey in Europe on nutrition and the elderly, a concerted action (SENECA). Am J Clin Nutr 82: 879-886 https://doi.org/10.1093/ajcn/82.4.879
  10. Cao G, Prior RL (1998): Comparison of different analytical methods for assessing total antioxidant capacity of human serum. Clinical Chemistry 44(6): 1309-1315
  11. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL, Jones DW, Materson BJ, Oparil S, Wright JT Jr, Roccella EJ, National Heart, Lung, and Blood Institute Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure; NAtional High Blood Pressure Education Program Coordinating Committee (2003): The seventh report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure. JAMA 289(19): 2560-2572 https://doi.org/10.1001/jama.289.19.2560
  12. Chio JH, Kim MH, Cho MS, Lee HS, Kim WY (2002): The nutritional status and dietary pattern by BMI in Korean elderly. Korean J Nutr 35(4): 480-488
  13. Chio HJ, Kang DH, Kim GE, Cheong HS, Kim SH (2002): A study on nutritional status of the long-lived elderly people in Kyungnam. J Korean Soc Food Sci Nutr 31(5): 877-884 https://doi.org/10.3746/jkfn.2002.31.5.877
  14. Choe BK, Son LS, Yoon TY, Choi, Park SY, Lew DJ (1999): Association of anthropometric indices with prevalence of hypertension in Korea adults. Korean J Prev Med 32(4): 443-451
  15. Choe JS, Paik HY, Kwon SO (2004): Nutritional status and related factors of residents aged over 50 in longevity areas. I. Anthropometric and biochemical nutritional status. Korean J Nutr 37(9): 825-837
  16. Demirbag R, Yilmaz R, Kocyigit A (2005): Relationship between DNA damage, total antioxidant capacity and coronary artery disease. Mutat Res 570(2): 197-203 https://doi.org/10.1016/j.mrfmmm.2004.11.003
  17. Desai MY, Santos RD, Dalal D, Carvalho JA, Martin DR, Flynn JA, Nasir K, Blumenthal RS (2005): Relation of serum uric acid with metabolic risk factors in asymptomatic middle-aged Brazilian men. Am J Cardiol 95: 865-868 https://doi.org/10.1016/j.amjcard.2004.12.013
  18. Franzoni F, Ghiadoni L, Galetta F, Plantinga Y, Lubrano V, Huang Y, Salvetti G, Regoli F, Taddei S, Santoro G, Salvetti A (2005): Physical activity, plasma antioxidant capacity, and endotheliumdependent vasodilation in young and older men. Am J Hypertens 18: 510-516 https://doi.org/10.1016/j.amjhyper.2004.11.006
  19. Hansel B, Giral P, Nobecourt E, Chantepie S, Bruckert E, Chapman MJ, Kontush A (2004): Metabolic syndrome is associated with elevated oxidative stress and dysfunctional dense high-density lipoprotein particles displaying impaired antioxidative activity. J Clin Endocrinol Metab 89(10): 4963-4971 https://doi.org/10.1210/jc.2004-0305
  20. Jeon CH, Lee EH, Lee HI (1998): Blood total antioxidant capacity in 358 patients with stomach and colorectal cancer. Korean J Clin Pathol 18(2): 151-155
  21. Kashyap MK, Yadav V, Sherawat BS, Jain S, Kumari S, Khullar M, Sharma PC, Nath R (2005): Different antioxidants status, total antioxiant power and free radicals in essential hypertension. Mol Cell Biochem 277: 89-99 https://doi.org/10.1007/s11010-005-5424-7
  22. Kennedy G, Spence VA, McLaren M, Hill A, Underwood C, Belch JJ (2005): Oxidative stress levels are raised in chronic fatigue syndrome and are associated with clinical symptoms. Free Radic Biol Med 39(5): 584-589 https://doi.org/10.1016/j.freeradbiomed.2005.04.020
  23. Kim HC, Suh I, Lee KH, Jee SH, Kim CS, Nam CM (1999): Twelve-year incidence of hypertension and its risk factors in a lean population: the Kangwha Study. Korean J Prev Med 32(4): 435-442
  24. Kim JH, Kim MJ (2004): Dietary intakes and plasma antioxidant vitamins levels in Korean elderly with diabetes. Asia Pac J Clin Nutr 13: S152
  25. Kim MJ, Kim OH, Kim JH (2002): The effects of smoking, drinking 108 and exercise on antioxidant vitamin intakes and plasma antioxidant status in elderly people living in Ulsan. Korean J Comm Nutr 7(4): 527-538
  26. Kim SK, Park YS, Byoun KE (2000): Comparison of the total antioxidant status and usual dietary intake in normal and overweight males. Korean J Comm Nutr 5(4): 633-641
  27. Kim WK (1999): Effects of vitamin E supplementation on immune response and antioxidant defense parameters in healthy Korean elderly women. J Korean Soc Food Sci Nutr 28(4): 924-933
  28. Kim WY, Kim MH (2005): The change of lipid metabolism and immune function caused by antioxidant material in the hypercholesterolemic elderly women in Korea. Korean J Nutr 38(1): 67-75
  29. Kuzuya M, Ando F, Iguchi A, Shimokata H (2002): Effect of aging on serum uric acid levels: Longitudinal changes in a large Japanese population group. J Gerontol A Biol Sci Med Sci 57: M660-664 https://doi.org/10.1093/gerona/57.10.M660
  30. Kwak HK, Yoon S (2005): Relation of serum oxygen radical absorbance capacity with metabolic risk factors in human volunteers. J Comm Nutr 7(4): 215-219
  31. Lee JH, Kim EM, Chae JS, Jang YS, Lee JH, Lee G (2003): The effect of isoflavone supplement in plasma lipids & antioxidant status in hypercholesterolemic postmenopausal women. Korean J Nutr 36(6): 603-612
  32. Lee SE, Kim JH (2004): Comparison of dietary intakes and plasma lipid levels in diabetes and control elderly. Korean J comm Nutr 9(1): 98-112
  33. Lim JY, Kim OH, Kim JH (2006): Effects of antioxidant supplementation on lipid profiles in elderly women. Koream J Comm Nutr 11(1): 133-142
  34. Ministry of Health & Welfare (2002): 2001 National health and nutrition survey-Chronic diseases-, pp.4, 48
  35. Nagahama K, Inoue T, Iseki K, Touma T, Kinjo K, OHya Y, Takishita S (2004): Hyperuricemia as a predictor of hypertension in a screened cohort in okinawa, Japan. Hypertens Res 27(11): 835-841 https://doi.org/10.1291/hypres.27.835
  36. Ohkawa H, Ohishi N, Aogi K (1979): Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95: 351-358 https://doi.org/10.1016/0003-2697(79)90738-3
  37. Pesce AJ, Kaplan LA (1987): Methods in clinical chemistry. The CV Mosby-Company, ST. Louis Washinton DC, Toronto. Part 10, Chapter 75, pp.574-581
  38. Prior RL, Cao G (1999): In vivo total antioxidant capacity: comparison of different analytical methods. Free Radic Biol Med 27: 1173-1181 https://doi.org/10.1016/S0891-5849(99)00203-8
  39. Radon J, Oliva MR, Tormos C, Giner V, Chaves J, Iradi A, Saez GT (2003): Antioxidant activities and oxidative stress byproducts in human hypertension. Hypertension 41: 1096-1101 https://doi.org/10.1161/01.HYP.0000068370.21009.38
  40. Rice-Evans A, Miller N, Paganga G (1997): Total antioxidant status in plasma and body fluids. Method in Enzymology 234: 279-293
  41. Romero-Alvira D, Rochi E (1996): High blood pressure, oxygen radicals and antioxidants: etiological relationships. Med Hypotheses 46(4): 414-420 https://doi.org/10.1016/S0306-9877(96)90196-6
  42. Sagar S, Kallo IJ, Kaul N, Ganguly NK, Sharma BK (1992): Oxygen free radicals in essential hypertension. Mol Cell Biochem 111: 103-108
  43. Sharifian A, Farahani S, Pasalar P, Gharavi M, Aminian O (2005): Shift work as an oxidative stressor. J Circadian Rhythms 3: 15 https://doi.org/10.1186/1740-3391-3-15
  44. Suh HS, Lee CH, Park HS, Kim CJ (1993): Relationship of several obesity indices to blood pressure. J Korean Acad Fam Med 14(8-9): 594-600
  45. The Korean Nutrition Society (2000): Recommended Dietary Allowances for Koreans, 7th revision
  46. Touyz RM (2003): Reactive oxygen species in vascular biology: role in arterial hypertension. Expert Rev Cardiovasc Ther 1: 91-106 https://doi.org/10.1586/14779072.1.1.91
  47. Tse WY, Maxwell SR, Thomason H (1994): Holder antioxidant status in controlled and uncontrolled hypertension and its relationship to endothelial damage. J Hum Hypertens 8: 843-84
  48. Yang KM (2005): A study on nutritional intake status and health-related behaviors of the elderly people in Gyeongsan area. J Korean Soc Food Sci Nutr 34(7): 1018-1027 https://doi.org/10.3746/jkfn.2005.34.7.1018
  49. Zeman FJ (1991): Clinical Nutrition and Dietetics. 2nd Ed. New York: Publishing Company