Journal of the East Asian Society of Dietary Life (동아시아식생활학회지)

The East Asian Society of Dietary Life (동아시아식생활학회)
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Effect of Soybean Powder on Lipid Metabolism and Enzyme Activities in Induced Hyperlipidemic Rats

대두분 급여가 고지혈증 흰쥐의 지질대사 및 효소 활성도에 미치는 영향

  • Shin Mee-Kyung (Dept. of Food and Nutrition, Wonkwang University) ;
  • Han Sung-Hee (Dept. of Food of Nutrition, Wonkwang Health Science College) ;
  • Park Sung-Hye (Dept. of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University)
  • 신미경 (원광대학교 식품영양학과) ;
  • 한성희 (원광보건대학 식품영양과) ;
  • 박성혜 (원광대학교 한의학 전문대학원 한약자원개발학과)
  • Published : 2006.04.01
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Abstract

To investigate the effects of yellow soybean powder on serum lipid level and enzyme activities, male Sprague-Dawley(SD) rats were given hyperlipidemic diets for 6 weeks. Rats(n=8) were divided into three groups consisting the normal group(N), hyperlipidemic diets group(C) and hyperlipidemic diets and yellow soybean powder group(YSP). YSP group lowered triglyceride, total lipid, phospholpid, ester-cholesterol and free-cholesterl than control group. YSP group lowered total-cholesterol, VLDL-cholesterol and LDL-cholesterol but increased HDL-cholesterol of the serum compared to the control group. Athergenic Index(AI) and LHR(LDL-cholesterol/HDL-cholesterol ratio) of YSP group was decreased by control group (p<0.05). On the other hand, glutamic oxaloacetate transaminase(GOT), glutamic pyruvate transaminase (GTP), lactate dehydrogenase(LDHase) and alkaline phosphatase(ALP) enzymes activities were decreased by hyperlipidemic diets group (C). These results suggest that yellow soybean powder fed a lipid lowering effect in serum of rats.

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