Korean Journal of Medicinal Crop Science (한국약용작물학회지)

The Korean Society of Medicinal Crop Science (한국약용작물학회)
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Increase Effect of Anticancer Activities on Rhodiola sachalinensis A. Bor by the Change of Extraction Process

추출 공정 다변화를 통한 홍경천의 항암활성 증진효과

  • Kim, Cheol-Hee (School of Biotechnology and Bioengineering, Kangwon National University) ;
  • Kim, Hyo-Sung (School of Biotechnology and Bioengineering, Kangwon National University) ;
  • Kwon, Min-Chul (School of Biotechnology and Bioengineering, Kangwon National University) ;
  • Bae, Geun-Jung (School of Biotechnology and Bioengineering, Kangwon National University) ;
  • Ahn, Jup-Hee (School of Biotechnology and Bioengineering, Kangwon National University) ;
  • Lee, Hak-Ju (Divisoion of Wood Chemistry, Korea Forest Research Institute) ;
  • Kang, Ha-Young (Divisoion of Wood Chemistry, Korea Forest Research Institute) ;
  • Lee, Hyeon-Yong (School of Biotechnology and Bioengineering, Kangwon National University)
  • Published : 2006.12.30
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Abstract

This study was performed to compare effect of anticancer activities on Rhodiola sachalinensis by ultrasonifi-cation process and solvent. Compared the yield to the water extracts (WE), wafer extracts with ultrasonification (WEU) at60, loot and ethyl alcohol extracts (EE), ethyl alcohol extracts with ultrasonification (EEU) at 60 ${\circ}$C from Rhodiola sachalinensis. Experimental studies were progressed through the anticancer activities such as cell cytotoxicity, inhibition activities of cell growth. The cell cytotoxicity using human embryonic kidney cell (HEK293) was showed cytotoxicity of below 26.26%by extracts of Rhodiola sachalinensis in 1.0 mg/ml concentration, The anticancer activities were increased in over 70% by extracts of Rhodiola sachalinensis in A549, AGS, Hep3B and MCF-7 cells. From the results, the extract Rhodiola sachalinensis were showed useful anticancer activities.

Keywords

References

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