The Korea Journal of Herbology (대한본초학회지)

The Korea Association of Herbology (대한본초학회)
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The Effects of Artemisiae Capillaris, Ponciri Fructus and Cartaegi Fructus in Obese Rats Induced by High Fat Diet

고지방 식이로 유도된 비만 흰쥐에 인진(茵蔯), 지실(枳實), 산사가 미치는 영향

  • Ban, Sang-Seok (Dapartment of Oriental Medicine Graduate school of Daegu Hanny University) ;
  • Yoon, Hyeon-Deok (Dapartment of Oriental Medicine Graduate school of Daegu Hanny University) ;
  • Shin, Oh-Chul (Dapartment of Oriental Medicine Graduate school of Daegu Hanny University) ;
  • Shin, Yoo-Jung (Dapartment of Oriental Medicine Graduate school of Daegu Hanny University) ;
  • Park, Chi-Sang (Dapartment of Oriental Medicine Graduate school of Daegu Hanny University) ;
  • Park, Ji-Ha (Dapartment of Oriental Medicine Graduate school of Daegu Hanny University) ;
  • Seo, Boo-Il (Dapartment of Oriental Medicine Graduate school of Daegu Hanny University)
  • 반상석 (대구한의대학교 한의학과 본초학교실) ;
  • 윤현덕 (대구한의대학교 한의학과 본초학교실) ;
  • 신오철 (대구한의대학교 한의학과 본초학교실) ;
  • 신유정 (대구한의대학교 한의학과 본초학교실) ;
  • 박치상 (대구한의대학교 한의학과 본초학교실) ;
  • 박지하 (대구한의대학교 한의학과 본초학교실) ;
  • 서부일 (대구한의대학교 한의학과 본초학교실)
  • Published : 2006.09.30
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Abstract

Objectives : This study was designed in order to determine the effects of Artemisiae Capillaris, Ponciri Fructus and Cartaegi Fructus so as to care the obesity and obesity-related diabetes. Methods : After induction of obesity by high fat-diet in rats, the each extracts of three medicinal stuffs were administrated with continuous high fat-diet for 4 weeks. And the changes of lipid metabolism, liver function and blood levels of glucose and insulin were examined. Results : Blood concentrations of triglyceride, free fatty acid and LDL-cholestrol were increased in obese group compared with standard dieted group. By treatment of Ponciri Fructus or Cartaegi Fructus with high fat-diet, their concentrations of glyceride and free fatty acid were significantly decreased. Blood level of LDL -cholesterol was decreased in all stuffs treated groups, however atherogenic index was significantly decreased in treatment of Cartaegi Fructus with high fat-dieted group. Conclusion : High fat-dieted with treatment of Ponciri Fructus or Cartaegi Fructus, fatty degeneration was remarkably diminished.

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